Gastroscopy and colonoscopy are required for health checkups. Due to environmental pollution and changes in dietary habits, the incidence of gastrointestinal tumors has been increasing year by year in recent years, and is getting younger and younger, which seriously endangers human life and health. Most of the patients with gastrointestinal tumors are already in advanced stage when they are detected. Therefore, early detection of gastrointestinal malignancies is especially important. In Japan, gastroscopy has been listed as one of the routine medical checkups, while British medical doctors recommend that men over 40 years old should have gastroscopy and colonoscopy once a year. Studies have shown that it takes several years to develop from precancerous lesions to cancer, and if early cancer and precancerous lesions are detected and diagnosed in time during this period, they can mostly be treated and cured with minimally invasive endoscopy. Our gastroenterologists remind some high-risk groups, such as middle-aged people aged around forty years old and above; family history of tumor; chronic gastritis, moderate atypical hyperplasia, gastric bleeding, intestinal bleeding, gastric polyps, colon polyps, mucus stool and blood stool, etc., should increase the gastrointestinal examination during medical checkups or conduct separate gastrointestinal checkups, which are important for early detection, early diagnosis and early treatment of this type of disease, It is important for early detection, diagnosis and treatment of this type of disease. However, traditional gastrointestinal examination can cause certain discomfort and pain to patients, making many people afraid, especially children, hypertension and coronary heart disease patients, the discomfort and pain caused by the examination can lead to serious anxiety and non-cooperation, or induce serious complications, such as respiratory and cardiac arrest, therefore, the use of painless gastrointestinal microscopy is imperative. Painless gastroscopy is the appropriate application of sedation and anesthesia during gastroscopy treatment, so that the patient can complete the examination and treatment in a light sleep-like state. The whole process is comfortable, painless and memory-free for the patient. Under the supervision of anesthesiologists and nurses, the gastroenterologists operate the microscopy in the same way as ordinary gastroscopy. The advantages of painless gastroscopy are mainly the following four aspects: 1, allowing the patient’s whole body to relax and not be nervous before the examination, safe during the examination, no discomfort, and recover soon after the examination; 2, allowing the doctor to carefully examine all parts of the stomach and make a more accurate diagnosis, at the same time, it can also try to avoid possible damage to the digestive tract from the instruments when entering the mirror, which is beneficial to the judgment and treatment of the condition; 3, shortening the examination time 4.It helps to reduce complications caused by tension, fear and non-cooperation, such as cardiovascular system accidents, intestinal spasm, bleeding and perforation.