Consensus on the management of isolated pulmonary nodules (SPN)

  In this year’s CSCO continuing education session on lung cancer, Professor Yang Xuening of the Guangdong Lung Cancer Institute gave a presentation on “Consensus on the management of lung nodules”.  According to him, isolated pulmonary nodules (SPN) are a common type of lung disease based on high-resolution imaging. The detection rate of SPN is high in patients who smoke, and they have different or similar imaging presentations: solid nodules of various densities with thick and thin-walled cavities, hairy glass lesions (GGO), of which 91% of SPN containing GGO are malignant (JCOG0804/WJOG4507). Currently, the diagnosis of SPN is still in its infancy, and there is evidence that the combination of imaging and pathology can help improve diagnosis and standardize treatment.  The Lung Cancer Committee of the Chinese Anti-Cancer Association and the Lung Cancer Group of the Shanghai Medical Association’s Respiratory Disease Branch have introduced Chinese guidelines and consensus on SPN based on international guidelines and consensus: SPN diameter less than or equal to 4 mm, no risk factors without follow-up, 12 months follow-up if there are risk factors for lung cancer, no follow-up if stable; SPN diameter between 4 and 6 mm, 12 months follow-up if there are no risk factors, no follow-up if stable No follow-up required, 6-12 months for those with risk factors for lung cancer, then 18-24 months if stable; 6-8 mm SPN diameter, 6-12 months for those without risk factors, then 18-24 months if stable, 3-6 months for those with risk factors for lung cancer, then 9-12 months if stable, then 24 months; 8-30 mm SPN diameter If the SPN diameter was 8-30 mm, those with benign calcification or stable at 2 years of follow-up were not treated except for GGO, and the rest were judged for the probability of malignancy. If the probability of malignancy is less than 5%, low-dose spiral CT follow-up will be performed at 3, 6, 12, and 24 months; if the probability of malignancy is 5% to 60%, further examinations including enhanced CT, PET/CT, and needle aspiration biopsy will be performed; if the examination is negative, low-dose spiral CT follow-up will be performed at 3, 6, 12, and 24 months; if the examination is positive, VATS will be performed. Pathology will be performed; VATS will be recommended if the probability of occurrence is higher than 60%, and further radical resection will be required if it is malignant.