Endometriosis is still an enigma and a serious problem for many women. Menstrual pain, infertility, painful sex, many patients are familiar with these “major sins” of endometriosis, but what most people do not know is that endometriosis can also lead to “quiet” loss of kidney function. Patients with endometriosis should be treated as soon as possible after diagnosis and should have regular kidney function tests as well as kidney ultrasound and urine routine tests. Endometriosis can “block” the ureter: There are many causes of dysmenorrhea, and one of the most common causes is endometriosis. Endometriosis, as the name implies, is when the endometrium, which is supposed to stay in the uterine cavity, escapes and grows in other areas outside the uterine cavity. In general, there are three types of endometriosis: peritoneal, ovarian chocolate cysts and deep infiltrative endometriosis. In addition to causing dysmenorrhea, chronic abdominal pain, infertility, and infection, endometriosis may also lead to impairment of kidney function, which is particularly likely to be brought about by deep infiltrating endometriosis. Ectopic endometriosis can grow in the pelvic cavity; it may grow on the intestinal wall or around the ureter. In the most dangerous case, endometriosis lesions that grow around the ureter invade the ureter and cause ureteral obstruction, causing hydronephrosis and dilatation, which can lead to a silent loss of kidney function. Both ureters are usually rarely blocked at the same time. When one ureter is blocked, it causes damage to the function of this side of the kidney, but the other kidney works as usual. It is because of the strong compensatory nature of the kidneys that many patients may still have no symptoms when a significant percentage of one side of the kidney is damaged. If early hydronephrosis is not detected by timely examination, and when symptoms are present before seeking medical attention, it may have progressed to complete loss of kidney function on that side. Statistics show that there is a 5% chance of ureteral involvement in patients with endometriosis. Some readers may think that this is not a high percentage, but once it occurs it is difficult to treat, and the loss of kidney function due to severe hydronephrosis is almost irreversible, thus posing a great threat to the patient’s health by checking kidney function, urinary routine and kidney ultrasound regularly. Doctors diagnose endometriosis by performing ultrasound examinations of both kidneys to rule out ureteral obstruction, dilatation, and fluid accumulation. He also advised the patients themselves to pay attention to the monitoring of kidney function in the future. An annual check of renal function, renal ultrasound, and routine urine examination will help to detect the presence of endometriosis lesions involving the urinary tract in a timely manner. Nowadays, many units will check blood creatinine (kidney function) during physical examination. Although this index is important and can reflect the functional status of the kidneys, it cannot accurately reflect the kidney damage. The kidney has a strong reserve and compensatory capacity, when 40% of the 100,000 kidney units are damaged, the remaining kidney units may still work as usual; even if one kidney function is completely lost, the other kidney can compensate, so that the blood creatinine is still in the normal range. Only when more than 50% of the kidney units are damaged and the work of the remaining kidney units is insufficient to eliminate toxins from the body, blood creatinine will show abnormalities. Urine routine can make up for this deficiency. Urine routine can check for hematuria and urine protein, which can indicate the presence of kidney disease in a more timely and early stage, and the urine routine test is inexpensive and completely non-invasive. Ultrasonography is more likely to detect ureteral obstruction due to endometriosis and is the preferred method for timely detection of urogenital endometriosis. Early surgery is not recommended for long-term medication: For patients with endometriosis, in addition to close monitoring of kidney function, it is best to have surgery as soon as endometriosis is diagnosed. Prof. Yao Shuzhong introduced that surgery is the preferred method of treating endometriosis and the only way to remove the lesion. Some patients are reluctant to undergo surgery due to various concerns and prefer to opt for medication. It is true that medication may provide some relief, but it is completely ineffective in removing the lesion. Medications may also mask the severity of the disease, thus not detecting serious complications in time. Moreover, most of these medications are endocrine disrupting and are not recommended for long-term use by women prior to surgery. Even if they are used, they should be used after a thorough examination to exclude ureteral involvement obstruction and malignant lesions. The long-term presence of lesions in the pelvic cavity is a health hazard like a “time bomb” and increases the chances of kidney function damage. Finally, women are reminded that there is no good way to prevent endometriosis, but only to detect and treat it early. If you are suffering from menstrual cramps, painful intercourse and infertility problems, it is best to visit your gynecologist to rule out endometriosis. A small number of patients may not have any discomfort at all, so annual gynecological examinations and ultrasound examinations are very necessary. The doctor can detect nodules and adnexal masses, which are also the main signs of endometriosis, through manual examination, and facilitate early detection of the disease. Ultrasound examination can even detect early lesions such as chocolate cysts of the ovaries and ureteral obstruction and fluid retention.