Smoking has a great impact on the lungs and is one of the triggers of lung cancer, so some people have questions: how can smoking cause coronary heart disease when it is inhaled into the lungs? In fact, smoking and cardiovascular disease are also closely related. The incidence of coronary heart disease in smokers and passive smokers is 3.5 times higher than that of nonsmokers, the death rate is 6 times higher, and the incidence of myocardial infarction is 2-6 times higher. Thirty to forty percent of deaths from cardiovascular disease are related to smoking. Smoking has been recognized as one of the important risk factors for cardiovascular disease. The effects of smoking on coronary heart disease are mainly the following: 1. Smoking disrupts lipid metabolism and increases the degree of vascular atherosclerosis. Smoking can raise serum cholesterol, causing disorders of lipid metabolism, thus accelerating the degree of atherosclerosis of the vascular wall, while providing the material basis for the occurrence and development of coronary heart disease. Atherosclerotic plaque formation, like the “untimely bomb” in the blood vessels, once the unstable plaque rupture, will form a thrombus, which causes narrowing of the blood vessels or directly lead to acute heart attack, stroke or sudden death. 2, smoking increases myocardial hypoxia, aggravating the lack of blood supply to the heart muscle. After smoking, the blood carbon monoxide concentration increases, so that the blood hemoglobin and carbon monoxide binding rate increases, which will reduce the combination of oxygen and hemoglobin, thereby reducing the oxygen supply to the myocardium, resulting in increased myocardial ischemia and hypoxia. This is similar to gas poisoning, hemoglobin can carry oxygen, but if it carries a large amount of carbon monoxide, there is no room to carry oxygen, resulting in ischemia and hypoxia, but gas poisoning is passive ischemia and hypoxia, smoking is self-seeking tissue ischemia and hypoxia ah. 3, smoking increases the instability of atherosclerotic plaques, increasing the incidence of coronary angina and even heart attack. Myocardial hypoxia itself is one of the initiating factors of damage to the endothelial cells, smoking can make the endothelial cell permeability enhanced, thereby destroying the vascular endothelium, creating conditions for the aggregation of platelets and lipid deposition, prompting the formation of atherosclerosis, or make the formation of atherosclerotic plaque stability is destroyed, becoming the cause of angina or infarction. 4, smoking can increase the heart rate and blood pressure, increase myocardial oxygen consumption, increase the incidence of angina and heart attack. After smoking, can make the blood catecholamines rise, heart rate accelerates, blood pressure rises, and the same conditions, the faster the heart rate, the higher the blood pressure, the higher the myocardial oxygen consumption, will make the original myocardial blood supply is insufficient coronary arteries, increasing the chances of angina or infarction. Some studies have shown that the “culprit” causing the rise in blood pressure is nicotine in cigarettes, nicotine will make the blood vessel contraction enhanced, lumen thinning, blood flow decreased. Vasoconstriction, the resistance of small arteries is bound to increase, which leads to a gradual increase in blood pressure in normal people, and hypertensive patients further increase in blood pressure. 5, smoking can lead to vascular endothelial dysfunction, increasing the risk of vasospasm and increasing the chance of angina attack. After the damage of vascular endothelial function, the chance of vasospasm increases, which increases the chance of heart attack. The youthfulness of the population with coronary heart disease is evident to all. Clinically, coronary heart disease in the age of 30 is nothing new, and increasingly young patients with coronary heart disease are appearing in front of us. In most young people heart attack, vascular spasm accounts for a large proportion. In addition to coronary heart disease, smoking can also cause a variety of diseases: 1, cause thrombo-occlusive vasculitis; 2, induce sudden death; 3, reduce the body’s ability to sense the aura of heart disease; 4, increase the risk of abdominal aortic aneurysm; 5, cause osteoporosis; 6, lead to cataracts and macular degeneration; 7, cancer: in addition to lung cancer, but also include uterine cancer, bladder cancer, oral cancer, esophageal cancer, etc. 8, infertility; 9, affect the fetus.