1, pituitary tumor Gamma knife on pituitary tumor treatment purposes: control hormone level abnormalities, improve clinical symptoms; shrink or control tumor growth. Small pituitary tumor and optic nerve, optic cross, optic bundle distance greater than 3mm can be gamma knife treatment. Pituitary macroadenoma in older age or combined with other systemic diseases, poor systemic condition can not tolerate surgery, can be treated by fractional or block gamma knife. Recurrent pituitary tumors or residual pituitary tumors after surgery, especially if located in the cavernous sinus, are also good indications for gamma knife treatment. The control rate of pituitary adenoma is 92% to 97%; endocrine normalization is achieved in 20% of patients at 1 year, 32% at 2 years and 61% at 4 years. According to our experience, the improvement of endocrine needs a long-term process, and the required dose is higher than the dose for tumor growth control. 2.Auditory neuroma When the diameter of auditory neuroma is less than 3 cm, are suitable for gamma knife treatment, especially when the tumor diameter is less than 2.5 cm, gamma knife treatment effect is better than craniotomy. The long-term control rate of gamma knife for auditory neuroma is 95% to 97%. If the patient is older (over 60 years old), the tumor diameter can be relaxed to 3.5 cm. The advantages of gamma knife treatment compared with surgery are as follows: safe, non-invasive, painless; patients and their families do not need to experience the fear and concern of brain surgery; the rate of facial paralysis after gamma knife treatment is extremely low, about 2%. 3, trigeminal nerve sheath tumor small and medium-sized trigeminal nerve sheath tumor are suitable for gamma knife treatment. Gamma knife treatment effect is very satisfactory. The long-term control rate of gamma knife on trigeminal nerve sheath tumor is 91% to 98%. 4, meningioma Gamma knife treatment is mainly suitable for small meningioma, residual or recurrent meningioma after surgery, as well as small and medium-sized meningioma in the cavernous sinus, skull base and other parts. For small and medium-sized skull base meningioma or skull base meningioma residual after surgery, gamma knife treatment has been proven to be safe and effective. Through long-term follow-up, the control rate of Gamma Knife for such meningiomas is 93%-96%. 5, hemangioblastoma When the tumor is a small substantial tumor, gamma knife treatment is very effective. The long-term control rate of the tumor is about 80-90%. However, if the tumor has cystic changes, gamma knife can simply treat the tumor nodules. After surgery residual hemangioblastoma gamma knife treatment effect is good. 6, metastases intracranial single or several isolated multiple metastases, tumor diameter less than 3.5cm, intracranial pressure increase symptoms are not serious, are feasible gamma knife treatment. The purpose of gamma knife treatment is to locally control the tumor, relieve the symptoms, improve the quality of survival and prolong the life of the patient. The local control rate of gamma knife for metastases is about 93%. Gamma Knife can treat multiple times and multiple lesions at a time. For multiple metastases in the brain whether to combine with whole brain radiotherapy, there is still a debate. 7, glioma If the tumor remains or recurs after the patient has been treated with surgery, or radiotherapy and chemotherapy, the gamma knife can be used as an adjuvant treatment to kill the remaining tumor or recurrent tumor. If the tumor is small and deep, when the surgical treatment brings great damage to the patient, you can also gamma knife treatment 8, trigeminal neuralgia Gamma knife treatment is to irradiate the trigeminal nerve root with focused rays, the trigeminal nerve root is destroyed to prevent pain transmission into the conduction brain, the patient can not feel the pain. Six months after gamma knife treatment, the complete remission rate of trigeminal neuralgia is 65%. The rate of complete remission one year after Gamma Knife is 70%, and the rate of improvement in pain symptoms and complete pain relief is 80%-90%. Gamma knife high-dose irradiation of the trigeminal nerve root often causes facial sensory abnormalities.