Cholinergic urticaria after the appearance of face swelling can be improved through general treatment and medication to improve the symptoms, relieve discomfort, the treatment needs to be carried out under the guidance of a doctor. 1. General treatment: patients are advised to avoid scratching the face, and at the same time, light diet, abstaining from alcohol and smoking, regular work and rest, avoid staying up late, avoid overwork, maintain a relaxed state of mind, avoid tension and anxiety. 2. Medication: patients can apply local glycerine lotion or boric acid solution to relieve discomfort, but also can take anti-allergy drugs such as loratadine, cetirizine and other drugs to improve symptoms. Due to individual differences, there is no absolute most effective and safest drugs, it is recommended to strictly follow the doctor’s instructions to use, the emergence of adverse reactions to timely medical care, drug allergy is prohibited.