Current studies have shown that both Sinopharm Zhongsheng and Beijing Kexing’s vaccines showed varying degrees of antibody decline after 6 months of vaccination, the same as the regular vaccination pattern. Studies conducted by experts on whether to carry out booster vaccination found that the protective effect of booster vaccination on the vaccine can be improved from the point of view of immunogenicity. At present, it is recommended that high-risk groups can receive a booster shot: 1. The current situation of epidemic prevention and control in China is very good, focusing on external prevention of importation, and booster vaccination can be carried out for people at high risk of importation, such as staff of customs, border control, aviation, isolation points, and designated medical institutions, 6 months after completing the immunization program. 2. People with relatively low immune function and those over 60 years of age do not have the same immune effect produced by vaccination as The risk of serious illness, critical illness, and death is higher for people aged 18-59 years old who happen to be at high risk of infection than for other people. Therefore, it is recommended that a booster dose be given to this group of people 6 months after vaccination.3. It is also recommended that a booster dose be given after 6 months of vaccination if you travel to a high-risk area or country outside the country due to work, study, or exchange needs. The need for a booster immunization for the entire population after 6 months of vaccination at this stage is subject to further study and a comprehensive study should be made based on the epidemic situation.