Chemotherapy is one of the three major treatments for tumors and has a history of more than 60 years. During this period, after countless clinical observations and studies, it has confirmed its status in the treatment of advanced tumors, postoperative adjuvant therapy and preoperative adjuvant therapy, and is now widely used in the treatment of solid tumors, but chemotherapy has limitations, taking digestive tract tumors as an example. The efficiency of chemotherapy is only about 40%, and the current medical technology cannot tell us the specific people who are in the 40% and those who are not effective, but can only be known after treatment. 2, chemotherapy drugs also have certain killing effect on normal cells, mainly the fast growing cells are affected, such as blood, hair, nails, etc. In other words, that cell grows fast to kill that cell, because the tumor cells grow fastest, so kill it first. Therefore, the drugs applied in the clinic are after a lot of animal and human research to find a suitable dose: that is, to kill the tumor cells and make the normal cells tolerable. 3.At present, except for chemotherapy drugs (cytotoxic drugs), there are no other drugs that can directly kill tumor cells, including traditional Chinese medicine and targeted drugs. 4. Chemotherapy is a systemic treatment drug, while other drugs such as surgery, radiotherapy, radiofrequency, various knives, etc. are called local treatment. Therefore, the right time, right amount and right combination of these treatments is the principle of tumor treatment, i.e. comprehensive treatment! What patients and family members should understand are these limitations of chemotherapy, moreover, they should understand the individualization of tumor treatment, the treatment of each patient in the world is different, therefore, it is meaningless to discuss the treatment methods among patients, the positive energy of exchanging treatment experience and how to face is welcomed. Early diagnosis is the only possible cure! Due to the fact that people in China do not pay enough attention to the checkup and the eradication of bad habits in life at present, 60-80% of tumors in China are already in advanced stage once diagnosed, so most patients lose the chance of radical cure. We call on the society to strengthen the publicity and advocate the cultivation of good habits in life.