What are the things to pay attention to when a cirrhotic patient has an enlarged spleen? The most common causes of cirrhosis in our country today are hepatitis cirrhosis, alcoholic cirrhosis, schistosomiasis cirrhosis, drug-related cirrhosis and so on. Regardless of the cause of cirrhosis, it will cause a large proliferation of hepatocyte fibrous tissue, the texture of the liver becomes hard, and eventually there will be the formation of hepatocyte pseudobullets. With pathophysiological changes can cause compression of small bile ducts and small arteriovenous vessels within the hepatocytes. Poor bile excretion, obstruction of venous reflux, etc. The portal vein is the venous vessel that collects the superior mesenteric vein and splenic vein back into the liver. Once there is elevated vascular resistance, the pressure in the portal vein will increase, causing the spleen to become congested and enlarged, and in severe cases, hypersplenism may develop. Once the spleen becomes congested and enlarged, hypersplenism may develop. This can cause a decrease in the patient’s blood cell triplet system. Patients should reduce strenuous activities to avoid trauma causing rupture of the giant spleen and inducing fatal hemorrhage. Also, patients should eat soft, easy foods and avoid hard, coarse, indigestible foods that can cause ruptured esophagogastric fundic varices to bleed. Patients need to be reviewed periodically for routine blood tests for hematocrit. Platelet and red blood cell transfusions are given when necessary to treat anemia and thrombocytopenia. The most common clinical procedure is splenectomy. To reduce the damage caused by the giant spleen to the body.