Primary hand sweating is an abnormal hyper-secretion of sweat glands in the hands that is not affected by external temperature. It is a disorder of phytoconstriction caused by exocrine glands that results in excessive sweating in the palms, soles and armpits, which can affect social life and work. Thoracic sympathetic nerve block is currently the only effective and long-lasting treatment for hand sweating. Although hand sweating is not a major health problem, it can cause a lot of inconvenience and embarrassment in life, work and social interactions. People with sweaty hands have wet palms most of the time, and chronically wet hands often cause peeling. Teenagers of school age often get their exam papers wet due to excessive hand sweat, often before the papers are written. Teenagers are afraid to hold hands with others, and even shaking hands becomes a problem. As adults, they also have trouble with work and social activities. Although these are not serious diseases, excessive sweating puts patients in a state of helplessness, anxiety or panic every day, causing great inconvenience to their work, social and life, and seriously affecting their self-confidence. For a long time hand sweating non-surgical treatment (including astringents, antiperspirants, absorbents, sedatives, anticholinergic drugs, etc.), not only the efficacy is very little, but also because of its side effects and difficult to long-term application; so surgical treatment has become a major trend. The sympathetic nerve that controls the sweat glands in the hands is located in the second to fourth section of the thoracic spine (T2-4), and as long as this section of the thoracic sympathetic nerve is cut, the purpose of not sweating in the hands can be achieved. It is now recognized and proven that thoracic sympathectomy is the only effective and long-lasting treatment for hand sweating to date. The application of thoracoscopy has brought the treatment of hand sweating into a new historical period, as thoracoscopic surgery is less invasive, better revealed, accurately positioned, safe and reliable, and quicker to recover after surgery, thus, eradicating hand sweating is no longer a difficult and unacceptable treatment. However, many hospitals and physicians who can carry out thoracoscopic treatment of hand sweating now use three small triangular incisions (also called 3-hole thoracoscopy) on each side of the chest to place thoracoscopes and instruments to complete bilateral sympathectomy for hand sweating, which significantly reduces trauma compared to traditional thoracotomy, but still leaves two 1cm scar on both sides of the chest. In our thoracic surgery, we use single-port thoracoscopy to treat hand sweating; this procedure only requires a single tiny incision of about 1.0 cm in the concealed area of the axilla and removal of the bilateral T3 to T4 sympathetic nerves through a microscopic thoracoscope and instruments. The single tiny incision in the hidden area of the axilla is treated with cosmetic sutures, and the postoperative scars are small. Moreover, no chest drains need to be placed after surgery, which eliminates the pain and scarring caused by chest drains after surgery. The effect of the surgery is immediate, and the hands are warm, dry and sweat-free after the surgery, and all the worries and embarrassment caused by sweaty and wet hands in the past are gone immediately! The results are satisfactory and long-lasting. You can be discharged from the hospital the day after the operation, and the success rate of the treatment is as high as 99%.