High altitude reaction will have the effect of blood pressure fluctuation and blood pressure increase for hypertensive patients, and the symptoms of high altitude reaction include headache, dizziness, palpitation, chest tightness, shortness of breath, chest pain, anorexia, nausea, vomiting, etc. It can also cause the symptoms of lack of oxygen such as increased heart rate, and in serious cases, pulmonary edema or cerebral edema and other adverse consequences. Therefore, for patients with high blood pressure, they must take blood pressure regularly and systematically in the process of monitoring blood pressure, and if it is difficult to control blood pressure, they must choose a combination of drugs to reduce blood pressure, to reduce blood pressure within the normal range to prevent the adverse consequences of fluctuations or increases in blood pressure. In terms of drug selection, you can choose diuretics such as indapamide, calcium antagonists such as amlodipine, beta-blockers such as bisoprolol, angiotensin converting enzyme inhibitors such as benazepril, angiotensin II receptor antagonists such as valsartan, etc.