The main factors for the formation of facial pigmentation are: (1) disease causes, (2) endocrine disorders. (3) Genetics and external stimuli (e.g. sunlight). Therefore, in order to eliminate pigmentation, it is necessary to (1) enhance physical fitness and eliminate diseases; (2) keep the endocrine level in normal balance; (3) improve the blood rheology and local metabolic environment of the lesion area; (4) avoid external stimuli that produce pigmentation. Only in this way can skin discoloration not appear or disappear. Through the stimulation of acupuncture points, the metabolism of the whole body tends to be balanced, thus achieving the purpose of strengthening the body and preventing and treating diseases. The use of acupuncture point stimulation also has the advantage that drugs cannot match, which is its two-way regulation. Most of the hyper- and hypo-functioning of the body’s organs and the excess and deficiency of hormone secretion caused by endocrine disorders can be restored to normal levels through the stimulation of acupuncture points. The injection of drugs into acupuncture points can, firstly, enhance the strength of the drug’s action, so that small doses of drugs can play the role of large doses of drugs. Secondly, because the drug stays in the acupuncture point for a long time, the effect of the drug on the acupuncture point is prolonged and the therapeutic effect is strengthened. Thirdly, the complementary effect of drugs and acupuncture points on the body causes the dermal capillaries in the lesion area to dilate, thus improving the blood rheology and local metabolism in the lesion area. Therefore, skin discoloration can be eliminated through acupoint injection treatment.