Osteoarthritis, also known as degenerative arthritis, is a chronic, multiple disease of the joints, mostly in large joints throughout the body, such as the knee, shoulder, hip and ankle joints. In addition to degenerative changes, chronic strain, trauma or inflammation are also the causes of this disease. These diseases are mostly seen in middle-aged and elderly people, and joint pain, stiffness and dysfunction are the three main clinical symptoms. One or both joints are uncomfortable, painful and swollen, and after a period of inactivity, temporary stiffness may occur. Squatting function is severely restricted. The quality of life is seriously affected. For osteoarthritis, conservative treatments such as acupuncture, massage and physiotherapy can only relieve the symptoms; prolonged use of painkillers can stimulate the gastrointestinal tract and damage liver and kidney functions; and surgery such as joint replacement is difficult for patients to accept because of fear. ”With the help of C-arm positioning, joint fluid is extracted and the joint cavity is repeatedly irrigated with irrigation fluid, so that the inflammatory exudate and small debris of the diseased tissue are discharged. Ozone (O3), which has superb oxidizing power, is then repeatedly injected into the joint cavity, ligament attachment points and around the inflamed tissues. Ozone consists of three oxygen atoms, is light blue with a special odor, and has a superb oxidizing power. It inactivates or inhibits protein hydrolases and inflammatory cytokines in the joint cavity, reducing inflammation. It also induces the production of various superoxide enzymes, stimulates the proliferation of cartilage and fibroblasts, and plays a certain role in repair. At the same time, the “super laser” can improve circulation, eliminate inflammation and promote tissue repair by using its super penetrating ability. Through “joint ozone intervention”, various bone and joint diseases, including knee osteoarthritis, frozen shoulder, hip osteoarthritis, and ankle osteoarthritis, can be treated and restored to a functional state of freedom of movement.