Most pituitary tumors in the brain can be treated by minimally invasive nasal butterfly surgery, while a few require craniotomy, the cost of which varies according to the patient’s specific situation, and generally requires about 70-80,000 yuan. For example, some may damage the blood vessels during the craniotomy, causing a series of blood vessel rupture and bleeding, and need to use the appropriate hemostatic materials for proper repair, or even interventional repair, so that the corresponding costs will continue to increase, interventional embolization materials are very expensive. Another point to note is that because the reimbursement ratio of medical insurance differs from place to place, and craniotomy belongs to the scope of medical insurance reimbursement, it is better to ask the local doctor and medical insurance department, these are the factors that need to be considered.