Generally speaking, premature ovarian failure will have some effect on sex life. The amount of vaginal secretion is caused by the change of ovarian hormone secretion. Once the estrogen decreases, the vaginal secretion will decrease and the vagina will be dry, and the vaginal lubrication will be insufficient during sex, which will affect the quality of sex life. On the other hand, premature ovarian failure can also make women’s libido diminish, which in turn affects their sex life. Vaginal dryness can also lead to breakage of the vaginal mucosa during sexual intercourse, which can lead to viral and bacterial invasion and various vaginal inflammatory diseases that can affect sexual life.