With the aging of the society, the incidence of malignant tumors in the elderly population has been increasing, and most of the patients are predominantly in the advanced stage at the time of diagnosis, losing the opportunity for surgical treatment, making chemotherapy one of the main means. As the physical condition, physiological characteristics and organ functions of the elderly are different from those of adults in general, the clinic often again favors the use of aggressive and intense chemotherapeutic strategies, which usually results in low remission rate, high mortality rate, obvious toxic side effects, many serious complications and unsatisfactory quality of survival, reflecting how to reasonably solve the problems of treating the elderly patients with advanced tumors in the current stage of the chemotherapeutic level. For elderly patients with advanced tumors, appropriately prolonging the chemotherapy interval can reduce the toxic side effects and comorbidities of chemotherapy and improve the quality of life. In order to improve the therapeutic effect and remission rate, multi-drug combination, sufficient dose intensity and duration of treatment, and short cycle strategy are often adopted in order to achieve the purpose of killing tumor cells as much as possible, and this principle is more applicable to the patients who are young, with good physical condition and function of vital organs, as well as tumors sensitive to chemotherapeutic agents, such as malignant lymphoma and small-cell lung cancer, etc. However, the systemic condition of elderly patients is not good, and the interval of chemotherapy can reduce toxic side effects and comorbidities, and improve the quality of life. However, the systemic condition of elderly patients is poor, and they often suffer from cardiovascular and respiratory diseases, diabetes mellitus, and the compensatory ability of other important organs and systems is limited. In addition, there are not many tumors that can be cured by chemotherapy alone in elderly patients, and the low function of bone marrow and immune system makes elderly patients often suffer from severe bone marrow suppression and immunosuppression after intensive treatment or short-interval chemotherapy, which leads to serious infection or even sepsis and death, and also because of the cardiopulmonary, hepatic and renal function damage and insufficiency, metabolic disorders, and serious digestive function after short-interval intensive chemotherapy. Disorders. The common oral mucous membrane erosion and ulceration, low appetite, diarrhea, dehydration, mental instability, affecting normal feeding, digestion and absorption, causing extreme malnutrition, lack of protein and microelements, and the already low T-cell function and immunoglobulin of the elderly tumor patients are even lower, leading to the opposite result of the desire. Patients with short-interval chemotherapy suffer from long-term mental depression, low function and disorder of digestive tract, malnutrition, decreased physical condition and poor quality of life due to short intervals between chemotherapy treatments and insufficient time for recovery, which leads to fear of chemotherapy, while patients with long-interval chemotherapy recover their organ functions, especially digestive system, bone marrow, immune system and mental and physical strength because of relatively longer intervals between chemotherapy treatments, without serious toxic side effects. There are no serious toxic side effects, especially no serious infections and deaths during chemotherapy, and the quality of life is higher, so that most of the hard-to-cure elderly tumor patients can survive with tumors for a longer time. For elderly patients with advanced tumors whose current chemotherapy efficacy is not ideal, when formulating chemotherapy plans and programs, it should be clear that the purpose of treatment is palliative, and the decision of the specific program of treatment should not bring a great deal of risk and pain to the patient, and the gains and losses that may be caused by the treatment must be measured, and the restoration of the organ function of the host body should be emphasized at the same time that various programs and drugs are used to destroy the tumor cells, and arranging a good relationship between the attack and the tonic has become the strategy of tumor chemotherapy. The relationship between attack and tonic has become an important part of the tumor chemotherapy strategy. Appropriate extension of chemotherapy intervals, allowing patients to recover the functions of various systems to a certain extent and survive with tumor, avoiding serious toxic side effects and complications brought by multiple short intervals of chemotherapy, ensuring a more satisfactory quality of life and reducing the economic burden, is a safe and practicable therapeutic strategy for most of the elderly patients with incurable tumors at present.