Life and death are just a moment away

      In the early morning, all the medical staff of the emergency department stood neatly in the doctor’s office, and the short morning meeting held as usual was drawing to a close. In the distance, the siren of the emergency vehicle was approaching from afar, and in an instant it was at the door. “Receive the patient immediately!” The stretcher truck quickly pushed an 80-year-old male patient into the resuscitation room. The patient suddenly lost consciousness, his breathing and heartbeat stopped, and all his vital signs disappeared. A battle of life and death began quietly. The resuscitation work was carried out in an orderly manner. The green curve on the cardiac monitor, which symbolizes life, fluttered irregularly. “Ventricular fibrillation! 200 joules asynchronous electrical defibrillation!” The old man’s body jerked spasmodically under the electrode plate as the command was given in a low voice but at a very fast pace. My eyes were glued to the green curve, expecting the “life music” to appear, but to my disappointment, the green curve was still fluttering like nobody’s business.   The emergence of ventricular fibrillation, the most common form of sudden cardiac death in clinical practice, is a dangerous sign that the patient’s chances of survival are extremely slim. At this moment, the patient’s family was already outside the door, covering their faces and crying. Life is precious, but at this moment it is so fragile, so unbearable in front of the disease. However, I believe that life is great and strong, and I will never give up until the last moment, so I must do my best to save the patient. Intravenous channels, suction tubes, tracheal intubation …… various tubes were quickly established; epinephrine, dopamine, alamine …… had also been injected into the patient; 300 and 360 joules of electric defibrillation were completed within minutes one after another. At this point I saw the green curve begin to beat regularly, depicting the wonderful “music of life”. The patient was breathing on his own, and in that face, which was distorted by pain, a pair of eyes opened with great effort and looked around in amazement. CPR was successful! We all smiled at each other and shared our joy at this moment. However, we know that this is only the initial victory, the silent battle has just begun, more difficult work is waiting for us.         After further diagnostic analysis, the patient suffered from acute extensive anterior myocardial infarction, which is a very dangerous disease. It is caused by the formation of thrombus in the coronary artery, the blood vessel supplying blood to the heart, which blocks the vessel and suddenly occludes it. The treatment should dissolve the thrombus in the shortest possible time to reopen the occluded vessel to ensure the blood supply to the heart in order to ultimately save the patient’s life. The new battle-thrombolytic therapy starts immediately after a short preparation. The thrombolytic agent, recombinant tissue-type fibrinogen activator, is precisely pumped into the patient via a micropump. Death is still a constant threat to the patient’s life and danger is always with us. After 2 hours, the occluded blood vessel was reopened and the patient was saved, and a long-awaited smile appeared on the old man’s painful face.         Acute myocardial infarction is one of the most common acute and critical illnesses with high mortality in the emergency department. In the United States, 900,000 people suffer from acute myocardial infarction every year, and 225,000 of them die before being treated. Its incidence is also increasing year by year in China, causing great harm to the people. Since intracoronary thrombosis is the main cause of acute myocardial infarction, early treatment, early thrombolysis or intervention, and recanalization of the infarct-related arteries are the key to modern treatment of acute myocardial infarction. Results from large clinical trials examining 35-day survival in patients with acute myocardial infarction have shown a significant time-dependent effect of thrombolysis on mortality. Thrombolysis within 6 hours of symptom onset can save 35 lives per 1,000 people treated, while thrombolysis within 7 to 12 hours can save 16 lives per 1,000 people treated; thrombolysis >12 hours has little clinical benefit, or even does more harm than good, and is therefore no longer advocated. This shows that at this time, “time is heart muscle, time is life.” For this reason, we should call on all doctors to actively carry out thrombolysis or interventional therapy, and at the same time, we should popularize the knowledge of cardiovascular prevention and treatment among the public, and try to shorten the time between the consultation and the start of reperfusion, which will be of great importance to reduce the death rate and improve the quality of life of myocardial infarction patients. This is not only the duty of every medical worker, but also the cry for help from millions of AMI patients.