Panic eating watermelon on an empty stomach may be related to severe allergic reaction, acute gastroenteritis attack, renal insufficiency and other reasons. 1. Severe allergic reaction: If you are allergic to certain substances in watermelon, eating watermelon on an empty stomach, the body produces a severe allergic reaction, which can trigger panic. 2. Acute gastroenteritis attack: if you eat a lot of chilled or spoiled watermelon on an empty stomach, resulting in an acute gastroenteritis attack, because the gastrointestinal tract appears to be violent peristalsis and pain, there may be a manifestation of panic. 3. Renal insufficiency: Because watermelon contains a lot of water, patients with renal insufficiency eat a lot of watermelon on an empty stomach, so that the burden on the kidneys increased, resulting in abnormalities in the body’s circulatory system, and when the heart is involved, it will cause panic. If you eat watermelon on an empty stomach and have panic attacks, you should go to the hospital in time to receive treatment, so as not to cause adverse consequences.