Ankle swelling may be caused by the lack of blood circulation in the lower limbs due to prolonged standing position or sitting position. Patients can first massage the swollen area in the direction of the heart, or they can choose to apply ice packs to the swollen area within 48 hours to promote blood return and accelerate the elimination of swelling. In addition, ankle swelling may also be related to injuries to the joint capsule, muscles and ligaments that make up the ankle joint. The following 8 diseases are common in clinical practice: 1. ankle sprain: patients with ankle swelling and symptoms such as skin petechiae and restricted movement may be due to ankle sprain; 2. allergic reaction: allergic patients may show ankle swelling after contacting allergens, and the skin of the affected area in most patients will also 3, malnutrition: long time protein absorption disorder, excessive protein consumption, etc., caused by malnutrition patients, can appear the phenomenon of ankle swelling, edema can continue to appear to the femur, lumbosacral and other serious edema; 4, gouty arthritis: gouty arthritis caused by the increase of uric acid level in the body, often cause acute ankle swelling, accompanied by joint pain, redness, skin Rheumatoid arthritis: rheumatoid arthritis caused by the body’s autoimmune dysfunction can cause symptoms of ankle swelling. Generally, patients will feel swollen and stiff joints in the morning; 6, liver disease: liver is an important detoxification organ of the human body, liver disease will cause the body to reduce protein levels and increase the amount of tissue fluid exudation, which will lead to ankle swelling. Most patients with liver lesions also have yellowing of the skin and sclera; 7, kidney lesions: the kidneys are in charge of the excretory function of the human body, and kidney dysfunction can lead to water and sodium retention in the body, thus causing the symptoms of ankle swelling; 8, heart failure: heart contraction dysfunction leads to blood pooling in the veins, causing the symptoms of ankle swelling to occur, and the symptoms are more obvious at night. In addition, hypothyroidism, lower extremity venous thrombosis, diabetes, ankle synovitis and other disease factors may cause the above symptoms, which can be differentially diagnosed by a doctor.