Genital herpes can be very dangerous. Genital herpes can cause infertility in women in the most severe cases. Genital herpes is a well-treated disease, but after treatment genital herpes can easily come back. This is especially true in women who are pregnant and what the effects of genital herpes can be when it flares up during pregnancy. In our clinical work, we have noticed that some patients feel good about themselves, but in fact, medical tests suggest that their immunity is not high, and some even have a combination of immune deficiencies, and their symptoms often recur several times a year, which makes them more dangerous. On the other hand, pregnancy is a challenge for women and their own immunity changes, so to be on the safe side, pregnant women with a history of genital herpes are advised to have a blood immunology test to clarify their situation. For those pregnant women with low immunity, the virus enters the bloodstream causing viremia and the probability of disseminated infection is greatly increased. The pregnant woman may develop systemic symptoms as a result, causing damage to several organs of the body, which may threaten the life of the mother, not to mention the death of the fetus and miscarriage. In patients with normal resistance and limited symptoms (the vast majority of pregnant women fall into this category), the distribution of the virus in the mother is as follows: HSV is mainly confined to the site of the focal point of infection, that is, the genitals, perianal area, etc.; some of it can lead to peripheral lymphadenitis due to lymphatic reflux, but the infection is usually very limited and does not spread on a large scale; a small proportion can travel up the peripheral sensory nerves and lurk in the sacral nerves; the virus generally The virus does not enter the bloodstream and does not cause viremia. HSV does not spread to each other through blood between body organs; it neither reaches the placenta, nor can it enter the fetus through the placenta, so the effect of HSV on the fetus can not be discussed. According to a large-scale survey conducted in several countries over a period of 20 years, HSV infection in pregnant mothers does not increase the rate of fetal malformations and miscarriages compared to normal pregnant women. However, the results of animal studies are different from the findings, so this is still controversial in medical science. As we know, pregnancy is a special process during which the growth and development of the fetus in the womb can be affected by the slightest carelessness in the use of drugs. In general, genital herpes does not have a significant impact on the pregnant woman or the fetus. Therefore, the current clinical treatment of genital herpes during pregnancy is conservative and focuses on measures to relieve symptoms. In the absence of viraemia, pregnant women are advised to use mainly topical medications, such as topical antiviral drugs, until the symptoms disappear.