Typhoid fever is an acute intestinal infection caused by Salmonella typhi. Typical symptoms include persistent high fever, abdominal pain, hepatosplenomegaly, low white blood cells, a rose rash and relatively slow pulse in some patients, and indifference and unresponsiveness in severe cases. Typhoid carriers and patients are the only source of typhoid infection, Salmonella typhi is transmitted through the fecal-oral route, ingestion of contaminated food or water can cause the disease, and close daily contact with flies and cockroaches can also cause the spread and prevalence of typhoid. The population is generally susceptible to typhoid fever, with children and young people being more common, and a solid immunity can be acquired after the disease. Typhoid fever is mostly acute onset, generally by timely and effective antibacterial treatment can be cured, the disease mortality rate of about 1%-5%, the elderly, infants and children, malnourished people have a poor prognosis, the complication of intestinal perforation, intestinal bleeding higher mortality rate.