1. Which is better: thrombolytic therapy or coronary intervention after an acute myocardial infarction? Emergency coronary intervention for acute myocardial infarction is better than thrombolysis in terms of improving the recanalization rate of infarcted vessels, reducing the degree of residual stenosis, and decreasing the rate of re-occlusion and bleeding complications. The ability to open the infarct-related vessels early, adequately and durably is the key to the successful treatment of patients with acute myocardial infarction, especially for those patients with contraindications or unsuitable for thrombolysis, cardiogenic shock that does not respond to blood pressure-raising drugs, etc. Emergency intervention is preferable. However, in patients with an onset time of ≤6 hours, age <75 years old and no contraindication to thrombolysis, thrombolysis can also be considered if there is no condition for intervention. 2. Do I still need coronary intervention after thrombolysis? For patients who are not recanalized by thrombolytic therapy, remedial PTCA should be performed as soon as possible to recanalize the infarcted vessel. For patients with successful thrombolysis, although the vessel has been recanalized, there is a risk of re-occlusion, so interventional treatment is still needed to improve the residual stenosis. At present, immediate intervention is not recommended, but can be performed 7-10 days after successful thrombolysis. 3. What is coronary artery bypass grafting? Coronary artery bypass grafting (CABG), commonly known as coronary artery bypass grafting, is a procedure in which the patient's own saphenous vein or radial artery is used as bypass graft material, with one end anastomosed to the aorta and the other end anastomosed to the distal end of the diseased coronary artery segment, or the free internal mammary artery is directly anastomosed distally to improve the myocardial blood supply to the distal end of the coronary artery. 4.What types of patients with coronary artery disease are suitable for coronary artery bypass grafting? Grafting? The indications for coronary artery bypass grafting are: (1) left coronary artery trunk lesions; (2) severe coronary artery triple lesions with massive myocardial ischemia or poor ventricular function; (3) two or three vessel lesions, including severe lesions of the proximal left anterior descending branch; (4) multiple lesions combined with diabetes mellitus; and (5) simultaneous heart surgery such as valve replacement. 5.What are the high-risk factors affecting the success rate of coronary artery bypass grafting and what preoperative preparations should be made? What preoperative preparations should be made? Risk factors for coronary artery bypass grafting include: (1) advanced age; (2) respiratory, liver and kidney insufficiency; (3) poor cardiac function; (4) comorbidities such as diabetes and hypertension; and (5) other systemic diseases such as anemia and poor nutritional status. Adequate preoperative preparation is needed according to the patient's condition, such as treatment of lung infection, improvement of heart function, liver and kidney function, control of blood sugar, correction of anemia, etc. 6. How to choose whether to do coronary intervention or bypass grafting? Coronary intervention is suitable for single and double-branch lesions with moderate or greater myocardial ischemia that can undergo complete revascularization; lesions with high success rate of intervention, low surgical risk and low restenosis rate (e.g. short lesions with vessel diameter >2.5mm); multi-branch lesions that can undergo complete revascularization; patients with contraindications to surgical procedures; patients with acute coronary syndrome, especially acute myocardial infarction. Bypass grafting is suitable for patients with multiple lesions with poor left ventricular function for which interventional therapy cannot perform complete revascularization; diabetes mellitus with multiple diffuse lesions; left main stem lesions and anterior descending branch opening lesions with multiple lesions; and completely occluded lesions for which interventional therapy cannot be successful.7. Is it necessary to continue coronary artery disease treatment after successful coronary artery bypass grafting? Similar to coronary interventions, coronary artery bypass grafting only improves the blood supply to the distal end of coronary artery stenosis, while the atherosclerotic lesions in the rest of the vessels still exist. Therefore, it is necessary to continue the medication treatment for coronary artery disease after surgery, including antiplatelet therapy, lipid-lowering therapy, continued smoking cessation, and blood pressure and blood sugar control, in order to reduce the progression of atherosclerosis and the occurrence of restenosis in the bypass graft vessels.