SLE does not necessarily live beyond 20 years. SLE is an autoimmune disease for which there is no clinical cure, but with the advancement of medical technology the treatment of SLE has been greatly improved. Early diagnosis and early treatment can prevent or delay irreversible damage to tissues and organs and help improve the prognosis. SLE is one of the high-risk, high-mortality diseases, usually associated with genetics, environment or estrogen levels in the body. Patients with SLE often present with fever, fatigue and adverse symptoms such as loss of appetite and weight loss. The 1-year survival rate for SLE patients is 96%, the 5-year survival rate is 90%, and the 10-year survival rate has exceeded 80%. For patients with relatively mild symptoms, the chances of surviving for more than 20 years are also relatively high. Generally, as long as they actively cooperate with doctors for relevant examinations and treatments, they can return to normal life. However, there may be cases of poor cure, and with the further development of the disease, patients often suffer from heart failure or lung failure, which may even be life-threatening in serious cases. And for some patients with severe SLE, there is a high chance that they will die within 5 years.