Patients with hard skin a little like calluses on their tiger mouths may have calluses, chronic eczema, and possibly psoriasis, ringworm, and other problems. The patient may have a hard skin somewhat like a callus symptoms. You can follow medical advice to apply mometasone furoate cream or Denide cream and other drug treatment; 3, psoriasis: tiger mouth with hard skin a little like a callus may be psoriasis, may be related to genetic factors, environmental factors, patients may be accompanied by the symptoms of erythema covered with scales, you can follow medical advice to use tacrolimus ointment and pimecrolimus cream 1% treatment, but also by doing narrow-spectrum UVB phototherapy treatment; 4, ringworm. It is mainly caused by ringworm infection and may be accompanied by blistering and flaking. It can be treated by applying clotrimazole cream or ketoconazole cream as prescribed by the doctor, or by taking oral terbinafine hydrochloride tablets, itraconazole capsules and fluconazole capsules. Patients should pay attention to maintaining good habits in daily life, pay attention to keeping the skin of the hands clean and dry, and avoid scratching and tearing the skin to avoid injury, which may increase the risk of infection, pay attention to the combination of work and rest, and avoid overexertion.