Chinese medicine experience in the management of purpura nephritis

Allergic purpura nephritis is referred to as purpura nephritis, the onset of which is mostly in children and adolescents. Allergic purpura is a kind of allergic capillaritis, kidney damage is one of its basic symptoms, simple hematuria, hematuria with proteinuria is the most common manifestation of purpura nephritis. It is one of the most common manifestations of purpura nephritis. It has a long course and is prone to recurrence, which is one of the problems in nephrology. Western medicine mainly uses hormone therapy and looks for allergens to avoid it. However, the allergens are not detected in many patients, and the efficacy and side effects of hormone therapy are not satisfactory. I through long-term clinical practice experience, Chinese medicine has greater advantages for this disease, in the control of purpura and proteinuria and hematuria, improve the patient’s allergic constitution and other aspects have reliable efficacy, the clinical experience is introduced as follows: A, the name of the disease, the etiology of the understanding of the pathogenesis of Chinese medicine without the name of purpura nephritis, but from the main clinical manifestations of the disease, can be attributed to Chinese medicine ” Purple spots”, “epistaxis”, “grape disease”, “blood in urine” and other categories. The so-called epistaxis, as stated in the “Essentials of evidence and treatment? All Bloods”, “Blood comes out of the pores and is called epistaxis.” The so-called grapevine epidemic, as stated in “The Authentic Book of Surgery”, “Grapevine epidemic, which is mostly seen in children, feels the incorrect qi of the four seasons, depresses in the skin and does not disperse, forming small and large blue and purple spots, with the color of grapes, and develops all over the body and head.” Given that the bleeding sites of this disease are mainly epistaxis and blood in urine, the disease is mainly located in the lung, stomach, kidney and bladder. The cause of the disease is mostly blamed on external wind-heat and diet and fatigue, just as in the chapter of “The Beginning of the Birth of a Hundred Diseases in the Spiritual Pivot”, “If one eats a lot …… and does not live in a disciplined manner, and if one exerts oneself excessively, one’s luo veins are injured. Yang luo injury is blood outflow, blood outflow is epistaxis; Yin luo injury is blood within the overflow, blood within the overflow is after blood.” At the beginning of purpura nephritis, the pathogenesis is mostly actual heat evidence, due to wind-heat congestion of the lung, Yangming stomach heat congestion, heat forcing blood to move delicately, hair and muscle will be epistaxis. If the heat disturbs the kidney, then the blood is forced to go down, and it develops into blood in urine. Purpura nephritis is often prolonged and lingering, and the disease is prolonged and deficient. The TCM pathogenesis of this disease is mostly blamed on the deficiency of the spleen and kidney. The most common cause of purpura is the deficiency of the liver and kidney. The author has never used hormones in the treatment of purpura, but simply Chinese medicine for treatment. 1, instructed patients to avoid allergic food and drugs. The actual allergic purpura is caused by allergic to certain foods or drugs, and the diet is not controlled, nowadays children and adolescents purpura is caused by snacks, spicy and fried things. Drugs such as sulfonamides, penicillin, non-steroidal antipyretics and painkillers, and Remifentan should be avoided. 2. Pay attention to clear the heat of lung and stomach and cool the blood to dissolve the spots. “Purple spots” and “epistaxis” are lesions between the skin and muscles, according to Chinese medicine, “the lung is the master of skin and hair” and “the spleen (stomach) is the master of muscles According to Chinese medicine, “the lung is the master of skin and hair” and “the spleen (stomach) is the master of muscles”, and “the spots occur in Yangming” and “blood heat is delusional”. The pathogenesis is due to the heat in the lung and stomach, forcing the blood to move delicately, resulting in the blood overflowing outside the veins, which develops in the skin as purple spots. Qing? Huang Gongxiu’s “The Materia Medica Seeking Truth” cloud: “If the heat is not removed, the blood will not stop; if the heat is cleared, the blood will be safe”. The author has received satisfactory results by clearing the heat of the lung and stomach and cooling the blood to dissolve the spots based on the above theory. The first choice for clearing stomach heat is pungent, sweet and cold gypsum, the dosage is 30-60 grams, and it also enters the lung meridian to clear heat. If dry stools are seen, the appropriate amount of Rhizoma is added to draw the heat down from Yangming. To clear lung heat, choose scutellaria charcoal 15-20 grams, because the charcoal agent also has the function of stopping bleeding. The author often chooses fried gardenia to clear the fire of Sanjiao, clear heat and cool blood to stop bleeding, lead fire and heat downward, make it go away from the stool, and give the evil a way out; often add raw gypsum 30g-60g to clear the heat of Yangming’s qi, scutellaria charcoal to clear lung heat and stop bleeding; if there is Yangming’s internal organs, add raw rhubarb to cleanse the real heat and draw the heat from the bottom, if there is no internal organs, give cooked rhubarb to push out the new and draw heat downward. Cool the blood to resolve the spots. Ye Tianshi “warm fever theory” cloud: “into the blood on the fear of blood consumption and blood, straight must cool the blood to disperse blood”. The author often selects raw earth, tannin, dry lotus grass, comfrey, fried gardenia to cool the blood and stop bleeding, take raw earth, dry lotus grass, comfrey nourish Yin and clear heat, cool the blood and stop bleeding, tannin diarrhea blood in the volatile heat, cool the blood and disperse blood stasis, in order to prevent “stop bleeding stay stasis”, often add a small amount of salvia 3g-6g in the formula to cool the blood and blood. The treatment characteristics of the extension 1, improve the allergic constitution. The allergic purpura patients are mostly allergic, under the stimulation of allergens and induced the disease, so improve the patient’s allergic constitution is particularly important. The author often combined with allergy decoction to improve the allergic body on the basis of the identification of the prescription. Allergy Decoction is a folk formula for the treatment of urticaria, consisting of Chai Hu, Wu Mei Zi, Wu Wei Zi, Fang Feng and Sheng Gan Cao. The author used Yin Chai Hu to replace Chai Hu, and added Di Long to it, because it can not only clear lung heat, but also diuretic and laxative. Modern pharmacological studies have shown that Di Long has antipyretic, antihistamine and asthma calming effects. And modern pharmacological experiments have also confirmed that allergy decoction has anti-allergic effect. 2, flat tonic, clear tonic mainly, cautious use of warm drugs. In view of the performance of purpura nephritis with recurrent skin purpura, whether the kidney damage manifested by simple hematuria or hematuria with proteinuria, through clinical observation to its pathomechanical characteristics or deficiency of both qi and yin in favor of yin deficiency, or yin deficiency is predominant, so it is appropriate to supplement the deficiency with plain tonic or clear tonic. The so-called plain tonic means that when benefiting qi and nourishing yin, the amount of qi-enhancing products should not be large. The former is often used in the self-prepared purpura kidney 1 formula, the latter is often used in the self-prepared purpura kidney 2 formula. If purpura still occurs, then combined into the author’s special drugs to control purpura. Even if the patient has mild evidence of Yang deficiency, it is also prudent to use warm medicines, and it is more appropriate to use products that benefit Qi. 3, pay attention to keep the formula. The actual fact is that you can find a lot of people who are not able to get a good deal of money from the internet. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. To fight a “protracted war”, we need to keep the prescription in order to slow down the work. (1) good doctor-patient cooperation; (2) grasp the characteristics of their allergic body, allergy decoction throughout the treatment of the disease; (3) pay attention to the sleep, improve the patient’s confidence in treatment; (4) peaceful use of drugs, a long time to see the strange work. (4) gradually liberalize related foods to improve the quality of life of the guide. Because of more potential external allergens, in the case of allergens are difficult to detect completely, purpura nephritis patients if long-term strict dietary restrictions, life is very painful, and even to anorexia and lead to malnutrition. Therefore, patients with purpura nephritis are often instructed to gradually liberalize the relevant food to improve the quality of life and enhance their physical fitness after the purpura is completely controlled and the disease is in a long-term stable phase.