Hyperhidrosis (hyperhidrosis) mainly refers to patients who sweat more than normal and uncontrollably. It can be divided into primary hyperhidrosis and secondary hyperhidrosis. Botox has been shown to be effective in treating primary hyperhidrosis. These patients sweat mainly on the palms, armpits, head, face and cheeks. Hyperhidrosis is a common disorder, with epidemiological studies finding a prevalence of about 0.5-1% in young people. Although hyperhidrosis does not pose a great threat to one’s health, it can seriously affect daily life, work and social activities. For example, patients with hand hyperhidrosis usually have wet hands all year round, so they cannot engage in paperwork; patients with foot hyperhidrosis often have sweaty, white skin, which makes walking slippery and especially prone to bacterial infections and suffocating odors; as for patients with axillary hyperhidrosis. The suffering is even greater, the patient’s shirt is often soaked with sweat, emitting an unpleasant odor, people avoid it. Although hyperhidrosis is not a major disease, but the treatment is very difficult. There are a number of traditional treatments available, such as topical medication. Internal medication, physical therapy, and surgical treatment. Topical medication is generally required for 2-3 days for topical use, individual patients are still allergic to the medication, internal medication is prone to some side effects, surgical treatment has better efficacy for severe patients, but it is time consuming and costly surgery is also more painful. Botox treatment can be maintained for about six months with one injection, and the treatment is less painful. The principle of botulinum toxin treatment for hyperhidrosis is: sweat mainly comes from sweat glands, which are all innervated by sympathetic nerves, and acetylcholine can make sweat glands secrete, if the body’s acetylcholine secretion is blocked, sweat gland secretion will stop. The endotoxin injection can paralyze the sympathetic nerves in the sweating area, thus blocking or reducing the secretion of acetylcholine, and finally stopping the symptoms of excessive sweating in patients with hyperhidrosis. This treatment is safe and reliable, and complications are rare. Generally, the sweating is reduced within 48-72 hours after Botox injection, and the sweating disappears after 1 week.