1, anti-inflammatory and analgesic drugs There are many kinds of drugs in this category, because they can effectively inhibit the activity of prostaglandin synthase (cyclooxygenase), so that the synthesis of prostaglandin is reduced, so it can effectively relieve mild and moderate dull pain, such as joint pain, muscle pain, toothache, headache, menstrual pain, etc., especially for local non-bacterial inflammation both good pain relief, but also good anti-inflammatory effect. Therefore, these drugs have good anti-inflammatory, analgesic, antipyretic and anti-rheumatic effects, and are commonly used for the treatment of various acute and chronic pains, which generally do not produce dependence and tolerance. However, they are less effective for severe pain of trauma and visceral pain. (1) Anti-inflammatory pain: The commonly used dose is 25mg each time, 3 times a day. Use with caution in elderly patients with hypertension and gastric and duodenal ulcers. Anti-inflammatory pain suppositories can be administered rectally and absorbed directly by the intestinal mucosa, thus avoiding the stimulation of the drug to the gastrointestinal tract. (2) Fenbuterol: The commonly used dose is 300-600mg per dose, twice daily. (3) Fentanyl: the commonly used dose is 25mg per dose, 3 times a day; extended release 75mg per dose, 1 time a day. 2, central muscle relaxant Acting on the central nervous system of the multi-synaptic channels and produce muscle relaxation effect, for a variety of soft tissue contusion, sprain, muscle pain after exercise, muscle strain caused by pain, caused by central neuropathy muscle spasm and chronic fasciitis, etc.. Adverse reactions are mainly gastrointestinal symptoms such as nausea, followed by neurological reactions such as dizziness and drowsiness, which can be relieved after stopping the drug. (1) Clozoxazone tablets: the usual dose is 200mg per time, 3 times a day. (2) Myona: the usual dose is 50-100mg per time, 3 times a day. (3) Lysergic acid tablets: the initial dose for adults is 5mg per time, 3 times daily, with an increase of 5mg every 3 days and a maintenance amount of 30-70mg per day. 3. Diuretic dehydration drugs Diuretic dehydration drugs can eliminate acute nerve root inflammation edema, and have the effect of rapid symptom relief for acute attacks of lumbar spondylosis and lumbar intervertebral disc herniation. (1) 50% glucose solution: intravenous push, 20-40ml each time, 2-3 times a day. (2) 20% mannitol: commonly used as an intravenous drip, once a day, once every 8-12 hours in severe cases, must be pressurized fast drip, slow drip poor efficacy. (3) β-heptaosaponin: 20-30mg added to 500ml of 10% glucose solution intravenously, once a day. (4) Tachyphylaxis: commonly used 20mg intramuscular injection, once daily. Or 2omg orally, 2-3 times a day. 4.Hormonal drugs It has the effect of eliminating nerve root edema and relieving pain. Suitable for patients in the acute stage of lumbar spondylosis, without contraindications to hormones, often used in combination with dehydration. (1) prednisone: commonly used dose is 15-60mg per day, taken once at 8:00 a.m.; or take 2/3 of the amount in the morning, and then take the remaining 1/3 of the amount at night. (2) Dexamethasone: the usual dose is 1.5-3mg per dose orally, 1 dose in the morning, or 2 doses in the morning and 2 doses in the middle of the day, and 5-10mg per dose intramuscularly. (3) Chrysosomal: for local use, the usual dose is 10-20mg per dose, for painful points, joint cavity or epidural cavity closure of the vertebral canal. 5.Vitamin drugs (1) Vitamin B1: It can promote the energy supply of nerve tissue and improve the metabolism and function of nerve tissue. The common dose is 30mg orally 3 times a day and 100-200mg intramuscularly once a day. (2) Vitamin B6: It can synthesize the coenzyme of various transaminases, and has a certain role in the establishment and maintenance of cellular and humoral immunity, and can adjust the function of plant nerves. The common dose is 10mg orally 3 times a day. (3) Microphyllin: It is necessary for cell growth and division and for maintaining the integrity of myelin sheath of nerve tissue. The usual dose is 500μg orally 3 times a day and 500μg intramuscularly once a day. (4) Vitamin C: It is used in the synthesis of collagen and has the effect of scavenging free radicals. The common dose is 100-300mg orally 3 times a day. (5) Vitamin E: It is necessary to maintain the structure and function of skeletal muscle, smooth muscle and peripheral vascular system, and has the effect of enhancing the immune function and scavenging free radicals, and is often used clinically as an adjuvant in the treatment of myospasm, improving muscle strength and motor neuron disease. The usual dose is 100mg per day orally.