Impotence generally refers to erectile dysfunction, hyperlipidemia generally refers to hyperlipidemia, and erectile dysfunction may be related to hyperlipidemia in some way. Erectile dysfunction in men may have some relationship with hyperlipidemia. Because patients with hyperlipidemia can affect arterial blood flow due to the deposition of lipids in blood vessels, and even cause atherosclerosis, and the etiology of erectile dysfunction contains a vascular cause, that is, any disease that may lead to abnormal blood flow in the cavernous body, such as atherosclerosis, arterial stenosis, etc., can induce this disease. In addition to being associated with hyperlipidemia, erectile dysfunction is also associated with psychological factors, hypertension, obesity, penile sclerosis, severe glans, multiple sclerosis, uremia, trauma, hypogonadotropic hypogonadism, medication, and other factors, which should be differentiated. If one suffers from hyperlipidemia, one should also be alert to secondary myocardial infarction, coronary artery disease, diabetes mellitus and so on. It is recommended that patients with erectile dysfunction or hyperlipidemia actively go to regular hospitals and cooperate with the doctor’s treatment in order to promote the recovery of health.