Habitual miscarriage is defined as 2 or more consecutive spontaneous miscarriages, each occurring in the same month of gestation, with the same clinical course as general miscarriage, and is also called slippage in Chinese medicine.
What causes habitual miscarriage?
1, chromosomal abnormalities, including chromosomal abnormalities of both husband and wife and chromosomal abnormalities of embryo.
2, anatomical abnormalities, including uterine abnormalities and cervical insufficiency. Wang Liping, Department of Gynecology, Kaifeng City Hospital of Traditional Chinese Medicine
3.Endocrine abnormalities, including luteal insufficiency, polycystic ovary syndrome, hyperprolactinemia, thyroid function abnormalities, diabetes mellitus, etc.
4, Infection factors, such as mycoplasma, chlamydia infection, etc.
5, immune factors, such as closed antibody deficiency, abnormal lymphocytic factor, abnormal cell adhesion factor, abnormal natural antibodies (anti-cardiolipin antibody, anti-sperm antibody, anti-endometrial antibody, anti-ovarian antibody, anti-clear band antibody, anti-nuclear antibody), etc.
6, unknown causes, accounting for about 40%. Most of the spontaneous abortions with unknown causes were found to be caused by homozygous immune factors.
What are the clinical manifestations of habitual miscarriage?
1. Irregular vaginal bleeding in early pregnancy, often dark red or coffee-colored, without pregnancy discharge, followed by paroxysmal lower abdominal pain or low back pain.
2.Early pregnancy ultrasound shows an empty sac, i.e. no fetal bud and fetal heart are seen later.
3.Fetal growth restriction, i.e. fetal development is relatively delayed.
4.The fetus suddenly stops its heartbeat.
What tests are needed for habitual abortion?
1.Chromosome of both husband and wife.
2.Blood type of both spouses, including ABO blood type and RH blood type.
3.Closure efficiency.
4.Eugenics ten items.
5.The examination of natural antibodies such as anti-cardiolipin antibody, anti-sperm antibody, anti-endometrial antibody, anti-ovarian antibody, anti-hyaline antibody and anti-nuclear antibody.
6.Inspection of mycoplasma and chlamydia.