Gallbladder removal is commonly performed in cases of acute cholecystitis, chronic cholecystitis with obvious symptoms or gallbladder stones, as well as gallbladder polyps, gallbladder cancer, and gallbladder rupture caused by trauma. Some patients will experience biliary colic after gallbladder removal, accompanied by symptoms such as loss of appetite, abdominal distension and nausea, as well as vague or dull pain in the upper abdomen and right quarter rib area, and symptoms such as chills, high fever and jaundice, generally known as post-cholecystectomy syndrome. Since the gallbladder can store bile to participate in digestion, the bile that is still continuously secreted by the patient after gallbladder removal will be directly discharged into the intestine, which will easily cause the patient to develop symptoms such as alkaline reflux gastritis and indigestion, resulting in stomach pain, diarrhea and nausea after eating fatty food. However, most patients usually present with only a transient postoperative syndrome, and only a small percentage of patients require aggressive treatment. In addition, patients may experience immediate postoperative complications such as bleeding, subdiaphragmatic abscess, jaundice, and pancreatitis, as well as long-term complications such as bile duct stricture, biliary bleeding, and recurrent stones. Therefore, patients need to follow medical advice for bed rest and a light diet after surgery, fasting or gastrointestinal decompression if necessary, and they need regular follow-ups after surgery, and any physical discomfort should also be seen promptly.