Diabetes mellitus stage 4 may refer to diabetic nephropathy stage 4. Patients generally do not have a specific survival rate, and the survival time mainly depends on the degree of disease control. If the condition is well controlled, the survival rate will not be greatly affected, but if the condition is not well controlled, the patient will further progress to uremia leading to death. The life expectancy of patients with diabetic nephropathy is related to the patient’s physical condition, the degree of disease control, and psychological condition. If the patients actively cooperate with the doctor’s treatment, follow the doctor’s instructions to regulate the treatment of insulin injection, oral metformin and other hypoglycemic drugs, with low-salt, low-sugar, low-fat diet and moderate exercise, to control the blood glucose in the normal range, generally have little impact on life. However, if the patient does not actively cooperate with glucose-lowering treatment, the blood glucose is poorly controlled for a long time, and the condition progresses to uremia, which will affect the survival rate of the patient, and the seriousness of the condition may lead to the death of the patient. It is recommended that patients should go to the hospital in time after the symptoms of diabetic nephropathy stage 4 appear, so as not to delay the condition.