Meropenem belongs to the carbapenem class of antibiotics and is mainly used to treat various diseases caused by bacterial infections, such as pneumonia, urinary tract infections, biliary tract infections, meningitis, sepsis, etc. Meropenem has a broad antibacterial spectrum and a strong antibacterial effect, and it is effective for most bacterial infections, especially for severe infections without an etiological basis. Sometimes, in order to control the infection as soon as possible and prevent serious comorbidities, doctors may first use these drugs for treatment. However, meropenem is also ineffective against certain pathogens, such as a few highly resistant Klebsiella, maltophilic narrow-feeding Aeromonas, and methicillin-resistant Staphylococcus aureus infections, which have no therapeutic effect with meropenem. In addition, meropenem has no therapeutic effect on certain specific pathogens, such as mycoplasma, chlamydia, mycobacterium tuberculosis, and fungal infections. In addition, meropenem may cause adverse reactions, for example, because of its broad antibacterial spectrum, it is relatively easy to cause antibiotic-associated enteritis, leading to dysbiosis of the intestinal flora, and may induce bacterial resistance. Therefore, although meropenem has a strong anti-infective effect, especially in severe infections, it may have good efficacy, but it should not be used blindly, and a reasonable treatment plan should be chosen under the guidance of a doctor.