There are many Parkinson’s disease patients said, because of hand trembling, the whole body shaking, afraid of other people’s strange inquisitive eyes; because of the stiff limbs can not move, rarely go out, most of the time trapped in the home; after the disease, walking difficulties, many things can not do, children have a job, their respective families, my partner is not well, but also take care of me, feel like dragging their families. The slow aggravation of Parkinson’s disease makes patients gradually unable to take care of themselves and their physical and mental health suffers. Patients are prone to depression and low self-esteem, and some even refuse treatment and have a weak will to live. Studies have found that about 30% to 40% of patients with Parkinson’s disease are accompanied by depressive symptoms. Patients become frequently sad and depressed, indifferent to things around them, irritable, prone to crying, feeling poor health, having more discomfort, etc. The increased psychological burden will in turn aggravate the patient’s movement disorder. Therefore, when family members find that the patient is not talkative, does not want to see people, or is in tears, they must pay attention to it. The family members open up the patient and accompany the patient to see the doctor, the patient’s motor symptoms will improve and the depression will improve. In addition, family members guide the patient to think more on the bright side, encourage the patient to be optimistic and not to be hit by Parkinson’s disease, help the patient to make friends with some optimistic Parkinson’s patients, cheer each other up and encourage each other, and even participate in activities together, such as singing, partying, walking, playing Tai Chi, etc. Patients with well-controlled symptoms after surgical treatment with medication or a brain pacemaker can still do things they like, such as reading books, newspapers, raising flowers and plants, singing, playing chess, or other sports. Engaging in things that patients like can make them feel happy, which is beneficial to the treatment of Parkinson’s disease. Finally, family members need to be more patient when caring for the patient, more understanding and caring for the patient, more time for the patient, and cleverly resolve the patient’s psychological depression. Particularly severe depression can be treated with a combination of a small amount of antidepressants.