Pyrazinamide is an important anti-tuberculosis drug, and the course of treatment depends on the disease. For example, patients with primary treatment can usually stop using it for 2 months and switch to other drugs for consolidation, while replication TB may take about 3 months and drug-resistant TB may take 1-2 years. Anti-tuberculosis chemotherapy is the key to eliminating and controlling tuberculosis, and reasonable chemotherapy can kill bacteria in the lesions and promote healing. For milder cases and drug-sensitive Mycobacterium tuberculosis, including primary TB and tuberculous pleurisy, pyrazinamide can be given for 2-3 months. When the disease improves and clinical symptoms are under control, the patient will continue to take oral rifampin and isoniazid for a maintenance period of 4-6 months of consolidation therapy. If the patient develops gout symptoms while taking pyrazinamide, the drug should be reduced or discontinued for observation, and other treatment options should be adjusted. In addition, during the anti-tuberculosis period, patients need to maintain a good lifestyle, avoid staying up late, avoid smoking and drinking alcohol, strengthen nutrition to enhance physical fitness, pay attention to warmth and prevent catching cold.