There is no such thing as how to treat sciatica fastest, sciatica can be caused by lumbar disc herniation, . Spinal stenosis, pyriformis syndrome and other causes, can be taken according to the cause of drug treatment, surgical treatment, other treatment. 1. Lumbar disc herniation: If the sciatica is caused by lumbar disc herniation, non-steroidal anti-inflammatory analgesics such as diclofenac and celecoxib need to be used under the guidance of a doctor. Some patients can also be treated with spinal endoscopic nucleus pulposus removal, hemilaminectomy, simple intervertebral open nucleus pulposus removal. 2. Spinal stenosis: Sciatica caused by spinal stenosis requires the use of non-steroidal anti-inflammatory drugs such as indomethacin and acetaminophen, as well as neurotrophic drugs such as methylcobalamin and nerve growth factor under the guidance of a doctor. In addition, patients can also take lumbar posterior total laminectomy decompression surgery, lumbar posterior laminectomy decompression surgery. 3. Piriformis syndrome: For sciatica caused by piriformis syndrome, you can follow the doctor’s instructions to use meloxicam, ibuprofen and other non-steroidal anti-inflammatory drugs, and if necessary, you need to be injected with local anesthetics such as procaine, lidocaine, and other local anesthetics, as well as tretinoin, prednisolone acetate and other steroidal hormone drugs under the guidance of the doctor. In some cases, surgery may be performed to explore and relieve the nerve compression. In addition, patients may also take physical therapy such as ultrasonic shock, cold therapy, and heat therapy. Sciatica can also be caused by trauma, pregnancy, pelvic tumors, and other factors, and patients are advised to seek timely medical treatment under the guidance of a doctor.