Infectious lesion of the right lower lung means that the right lower lung location is attacked by pathogenic microorganisms such as bacteria, mycoplasma, and viruses, causing an inflammatory response in the right lower lung tissue. Special imaging changes of infectious lesions in the right lower lung can usually be detected by chest radiographs and CT examinations with abnormal values of laboratory tests or changes in vital signs associated with infectious diseases, which can be diagnosed as infectious lesions when combined with medical history and examination results. Imaging may show patchy, ground glass, or cavity-like changes in the right lower lung on CT and chest X-rays. There are differences in the imaging findings of right lower lung infectious lesions caused by different pathogenic microorganisms, such as the presence of dendritic signs and ground glass shadows in mycoplasma pneumonia and cavitation in Legionella. Infectious lesions of the right lower lung may cause abnormal laboratory test values for leukocytes, neutrophils, lymphocytes, serum, and calcitoninogen. For example, normal or decreased leukocytes and elevated lymphocytes may be seen in viral infectious right lower lung infectious lesions, and elevated leukocytes, neutrophils, serum, and calcitonin may be seen in bacterial or fungal infections. Treatment of infectious lesions in the right lower lung generally requires different anti-infective treatment options for different pathogenic microorganisms, such as amoxicillin and cefuroxime sodium if caused by bacteria, and erythromycin if caused by mycoplasma or chlamydia. If the infection is viral, antiviral drugs, such as ribavirin, can be used, and if it is caused by fungal infection, corresponding antifungal treatment, such as amphotericin B. If the clinical cannot accurately determine the specific pathogenic microorganism, patients over 18 years old can choose broad-spectrum antibiotics, such as moxifloxacin, levofloxacin, etc. for treatment.