The survival time of esophageal cancer in late stage depends on factors such as the depth of tumor infiltration and the scope of metastasis, which needs to be analyzed on a case-by-case basis. Esophageal cancer is a malignant tumor of the digestive system, which can spread in late stage and can be divided into local infiltration and extensive metastasis. If focal supraclavicular lymph node metastasis is also considered as advanced esophageal cancer, but it can be controlled by radiotherapy and other treatments, and the general survival period may be 2-3 years or even longer. In case of extensive metastasis, such as the tumor has metastasized to the chest, abdominal cavity or even bone when diagnosed, the survival period of most patients with advanced esophageal cancer may only be six months to one year if the vital organs are threatened. Patients with advanced esophageal cancer need to maintain a good state of mind, actively cooperate with doctors’ treatment and do well in daily life care to improve life quality and prolong survival time.