In the past, it was impossible to see the strong left ventricular spot due to the machine, but now the ultrasound machines in hospitals are advanced, and what could not be seen before can be seen, which makes many mothers-to-be very worried. In fact, fetal intraventricular dotted strong echogenicity is a sonographic manifestation rather than a cardiac malformation, let alone a diagnosis of cardiac abnormality. However, because it is often seen on ultrasound, the incidence of realistic intracardiac strong echogenic dots on the sonogram in midterm pregnancy is about 2.1-5%, with some reports ranging from 0.5% to 20%. The mechanism of the occurrence of intracardiac strong echogenic spots is not completely understood, but there are several explanations: 1. strong echogenic reflection formed by intraventricular tendon thickening. 2. 2, Central papillary mineral deposition. 3, Possible early ischemic changes in the terminal branches of the coronary arteries within the papillary muscle. 4.It may be an incomplete perforation of the papillary muscle tendon cords. This perforation can be a variation in the development of normal atria and ventricles, and most of the strong echogenic points gradually blur, shrink, or even disappear as the gestational months increase. Statistically, the left ventricle is significantly more likely to have strong echogenic points than the right ventricle, and they can occur simultaneously (1.5%-7.6%). In a few cases, two or three strong echogenic points, similar to bone echogenicity but without acoustic shadowing, may be present, with a diameter between 1 and 6 mm, located near the papillary muscle or tendon. The strong echogenic points seem to be suspended in the heart cavity and move with the contraction and diastole of the ventricles. Most of the strong echogenic points decrease in size and intensity as the gestational week progresses. They disappear almost completely by full-term gestation, but in some cases they may persist until delivery and can even be observed on postpartum ultrasound. In most fetuses, the intraventricular dots may not be of clinical importance. The strong echogenic point is usually calcification, and it can be said that this strong point is basically 99.0% okay, so don’t worry. The possibility of strong spots due to chromosomal variation is only 0.5% – 1%. Most of the glare spots are not problematic, and this is not clinically relevant. However, it has been found to be present in other intra- and extra-cardiac anomalies such as congenital heart disease, cervical hyaline thickening, transventricular hydatid tumor, ventricular dilatation, cerebral bulge, intestinal echogenicity, renal pelvis dilatation, finger and toe abnormalities, growth retardation, and chromosomal abnormalities. The relationship between intraventricular glare and fetal haploid anomalies: single glare in the left ventricle is more common, and the likelihood of fetal haploid anomalies is only 0-1.8 percent. The risk of fetal haploid anomalies is increased with multiple or significant glare in the right ventricle or both ventricles, and fetal karyotype analysis should be performed when available. There is no clear relationship between fetal intraventricular glare and fetal congenital cardiac anomalies and other non-chromosomal anomalies. The incidence of chromosomal abnormalities in fetuses with intracardiac dots is about 1/600 when the maternal age is ≥31 years. The incidence of chromosomal abnormalities in fetuses with intracardiac dots is about 1-5%. The chance of combined intracardiac strong echogenic spots with fetal anomalies is 20%-24%, including chromosomal anomalies without structural anomalies of resolution (4%-19%), chromosomal anomalies combined with anomalies at other sites (17%-19%) and chromosomally normal fetal anomalies ()63%-78&). Differential diagnosis: Intracardiac strong echogenic spots are generally not easily confused with other cardiac diseases, but may sometimes resemble small incipient ventricular tumors. However, sonographically the tumor is always attached to the septum or ventricular wall, and on follow-up ultrasound the tumor will gradually increase in size, while the strong echoes will gradually decrease or disappear.