Rheumatoid arthritis, also known as rheumatoid (RA), is a chronic systemic inflammatory disease of unknown etiology, with chronic, symmetric, multisynovial arthritis and extra-articular lesions as the main clinical manifestations, and is an autoimmune inflammatory disease. The disease occurs in small joints of the hands, wrists, and feet, with recurrent episodes and a symmetrical distribution. The early onset of rheumatoid arthritis often has systemic symptoms, such as fever, fatigue, poor diet, general malaise, etc. In severe cases, the disease may be accompanied by anemia. The main clinical manifestations are arthropathy, which is often symmetrical and involves small joints, with the proximal interphalangeal joints of the hands, wrist joints, and pleural toe joints of the feet being the most common, with serious spread to large joints such as elbows, shoulders, ankles, knees, and spinal joints. In the late stage, patients mainly suffer from joint dislocation, subluxation, deformation, and serious impairment of activities, and they cannot take care of themselves. The prevalence of rheumatoid arthritis is 0.32%-0.45% in our population. At present, there is a deeper understanding of the pathogenesis of rheumatoid arthritis itself, has developed and produced a variety of effective drugs, especially with the introduction of biological agents, patients can receive timely and effective treatment, the vast majority can be completely remitted. Prevention and treatment principles: 1, the correct understanding of rheumatoid arthritis: the current drugs can not only eliminate the symptoms, but also effectively block the progression of the disease, the prognosis depends on the early and late treatment and long-term uninterrupted effective treatment. 2, early diagnosis, early treatment, after the diagnosis should be combined with the use of anti-rheumatic drugs to improve the condition 3, if there is no contraindication, regardless of the stage of the disease, as long as the inflammation has the activity can be treated with biological agents 4, non-steroidal anti-inflammatory drugs can improve the symptoms, but can not improve the condition, so can not be used alone. 5.Chinese herbal medicine can improve the symptoms, there is no evidence to confirm that it can inhibit bone destruction, so it can not be used alone. 6.See a rheumatologist and follow up regularly to prevent adverse drug reactions. 7.It is advisable to rest at home during the acute period and do less activities; do appropriate exercises during the remission period to enhance the function of joints and ligaments. 8.If hip and knee joint destruction has occurred, joint replacement surgery can be done, and knee synovitis, in case of unsatisfactory drug treatment, arthroscopic synovectomy treatment can also be done.