Generally speaking, thigh soreness is not a precursor of cancer, and clinicians cannot diagnose the disease with a single symptom. Soreness in thighs is generally considered to be caused by cold stimulation or over-exercise resulting in local lactic acid accumulation or muscle strain, which can be gradually relieved after warm treatment or rest and massage. If we exclude the influence of physiological factors, the clinical symptoms of thigh pain may be caused by lumbar disc herniation, myofasciitis, rheumatoid, hip osteoarthritis, hip osteoarthritis, knee osteophytes and other diseases, which can be diagnosed differently after improving relevant examinations. Although patients with bone tumor may also have symptoms of localized thigh pain in early stage, but the pain is not obvious in early stage and is intermittent, with tumor invasion, it may develop into persistent pain. Therefore, if thigh pain persists without relief or worsens, it is recommended to seek medical attention in time, and the preliminary diagnosis can be made by X-ray or CT examination. In addition, the early manifestations of different cancers are different, and many cancers have no obvious precursors in the early stage, but may show systemic or local symptoms such as weight loss, fatigue, recurrent fever and cough. If you are worried about your health condition, it is recommended to seek medical treatment and improve the examination in time. Clinical diagnosis of cancer needs to combine the patient’s symptoms and signs, imaging test results, laboratory test results and pathological test results, so as to make a comprehensive judgment.