Compared with other causes of stroke, stroke due to atrial fibrillation is more frightening, with high rates of death, disability, and recurrence. According to the data, the mortality rate of stroke caused by atrial fibrillation can be 25% within 30 days, 50% within one year, and 73% in the acute phase. Patients with atrial fibrillation must be aware of stroke prevention and should make stroke prevention a top priority. They should pay attention to and self-test their stroke risk, and promptly administer anticoagulation therapy to help reduce the risk and harm of stroke. Mr. Liu, 46, had symptoms of panic and shortness of breath in February this year, went to the hospital and was diagnosed with atrial fibrillation, and was hospitalized for a sudden stroke in early May. Mr. Liu’s wife did not understand why her husband suddenly had a stroke. Stroke is caused by atrial fibrillation. When atrial fibrillation occurs, the contraction of the atria is weakened and the blood in the atria cannot be pumped out completely and stagnates in the atria, which will gradually clump together and form a thrombus. If the clot enters the blood vessels in the brain, it can easily block the blood supply to the brain and lead to a stroke. Therefore, atrial fibrillation is the cause, stroke is the effect, and thrombus formation is the culprit. Data show that nearly 1 in 100 people aged 40 and above will develop atrial fibrillation. The main symptoms of atrial fibrillation are palpitations, dizziness, syncope and shortness of breath, but some patients have no symptoms at all. Patients with atrial fibrillation have a nearly 5 times higher risk of developing stroke compared to those without atrial fibrillation. Director Mei emphasized that anticoagulation is a direct measure to reduce the occurrence of stroke in patients with atrial fibrillation and is one of the important treatment strategies for patients with atrial fibrillation. Therefore, once atrial fibrillation is diagnosed, patients should be concerned about their risk for stroke and the pros and cons of taking anticoagulants. For the average patient with atrial fibrillation, a self-assessment against the Atrial Fibrillation Stroke Risk Stratified Assessment Scale (CHADS2 score) is sufficient to know one’s risk of stroke based on the score. This scale has a total score of 6, with 4 points for each factor of age ≥75 years and having heart failure, hypertension, and diabetes, and 2 points for previous stroke, transient ischemic attack, or provincial embolism. The higher the score, the greater the risk of stroke, and patients can take active measures accordingly to eliminate the occurrence of stroke. Many patients with atrial fibrillation take aspirin for prevention. Aspirin prevents thrombosis by reducing platelet aggregation and is more effective in thrombosis caused by atherosclerosis. In contrast, clots caused by atrial fibrillation are mainly caused by clotting factors, so the efficacy of aspirin is limited. In the past decades, the commonly used anticoagulant in clinical practice was warfarin, but due to the large adverse effects and the difficulty in controlling the dose, patients need to go to the hospital regularly for blood sampling and monitoring, which is very inconvenient. In particular, most patients with atrial fibrillation are middle-aged and elderly, usually combined with hypertension and diabetes mellitus, which are more likely to lead to stroke if they do not use anticoagulants, but the use of anticoagulants greatly increases the risk of bleeding. This is a difficult problem in the clinical treatment of atrial fibrillation. In order to solve this problem, Director Mei’s team has developed Mei’s ultra-minimally invasive atrial fibrillation treatment, which completely eliminates the risk of thrombosis and stroke by surgically treating atrial fibrillation and removing the left heart ear at the same time, with a success rate of about 90% to 95% and a low recurrence rate. Lifestyle changes in patients with atrial fibrillation, such as exercising more, quitting smoking and drinking, avoiding caffeinated beverages, monitoring their blood pressure and cholesterol levels, and following a low-salt and low-fat diet, can help prevent strokes.