As the population grows and life expectancy increases, cardiovascular disease will continue to be the leading cause of death worldwide, and hypertension is the “invisible killer” of the heart. Once you have hypertension, coronary heart disease often follows! Epidemiological studies have shown that hypertension is an independent risk factor for coronary heart disease. The morbidity and mortality of coronary heart disease increase with blood pressure levels, and there is a continuous linear relationship between blood pressure levels and the risk of coronary heart disease in the entire population. Epidemiological studies have shown that a long-term increase in diastolic blood pressure of 5-6 mmHg increases the risk of coronary heart disease by 20-25%, and the risk of coronary heart disease is 5-6 times higher in those with diastolic blood pressure >110 mmHg than in those with diastolic blood pressure <80 mmHg. The results of the recent Eastern Stroke and Coronary Heart Disease Collaborative Study showed that the correlation between blood pressure and the incidence of cardiovascular events in Eastern populations was higher than in Western populations, and that blood pressure levels were linearly associated with mortality from coronary heart disease, meaning that efforts to control hypertension could reduce the incidence of cardiovascular events. Chronic hypertension can lead to left ventricular hypertrophy (LVH), myocardial interstitial fibrosis and, promote coronary atherosclerosis, causing functional and structural lesions of the coronary circulation. A sudden rise in blood pressure may cause plaque rupture and dislodgement, forming a thrombus, leading to a heart attack or even sudden death. Thus, poorly controlled hypertension and the dangers of hypertension are a red flag for the heart. Therefore, how to further reduce the risk of coronary heart disease and death in patients with hypertension is an important issue facing the treatment of hypertension. Control of blood pressure up to the standard, strengthening intervention on other risk factors of coronary heart disease, paying attention to the choice of drugs that provide more protection to the heart and other treatments are should be considered comprehensively.