According to the current Guidelines for the Treatment of Epilepsy in China, there is no concept of grand mal seizures. For these patients, the first aid treatment is to prevent suffocation and accidental injury. The family can turn the patient’s head to the side, loosen the collar to ensure a clear airway, and immediately call 120 emergency number to wait for rescue. At the same time avoid pressing the patient with force, during the waiting period for rescue you can put gauze and other items into the patient’s upper and lower teeth to avoid the patient’s tongue bite to avoid accidents. 1. prevent asphyxiation: keep the head to one side during the attack, and untie the patient’s tie and clothespin, remove dentures to maintain a clear airway, give oxygen inhalation if possible, and pay attention not to feed water and food to avoid triggering choking or asphyxiation; 2. Prevent accidental injuries: pay attention to the protection of the patient, you can remove sharp objects from the patient to prevent accidental injuries, and pay attention to not pressing the patient with excessive force to avoid fractures. In addition, because epileptic patients are prone to bite their tongues during the onset of epilepsy, gauze or rubber sheets can be placed between the patient’s upper and lower teeth to be prepared; 3. Drug therapy: If the patient is in an institution or a place with medical conditions, drug therapy can be given. The current clinical research recommended drugs are benzodiazepines, including lorazepam, diazepam, midazolam, the most commonly used in domestic clinics is diazepam, can be repeatedly injected, but need to pay attention to the risk of respiratory depression, need to be prepared in advance for tracheal intubation mechanical ventilation. If the effect is not good, intravenous midazolam, propofol and other anesthetic drugs can also be used; 4. Other treatment: If the patient has symptoms such as dehydration and elevated cranial pressure, targeted treatment, including reducing intracranial pressure, is required under the guidance of a doctor. If symptoms of hyperthermia occur, physical means are needed to cool the body, such as warm water wiping the body surface. In addition, patients need to actively prevent infection. When the patient is stable, he or she should visit a hospital epilepsy clinic and take antiepileptic drugs regularly. If there is no dedicated epilepsy clinic, he or she can also visit a neurology or neurosurgery clinic.