Palpitations, panic, fatigue and shortness of breath can not be ruled out due to physiological factors, or disease factors such as coronary heart disease, asthma and other symptoms. 1. Physiological factors: the patient usually due to the inner spirit of anxiety and lead to nervous dysfunction, nervous dysfunction usually affects the cardiovascular function, due to insufficient blood supply leads to pain in the heart area and accompanied by palpitations and other symptoms. Or short-term shock, nervousness may also lead to palpitations and panic attacks. 2. Disease factors (1) Coronary heart disease: this is usually due to the heart function is not good resulting in insufficient blood supply and thus lead to overloading of the heart muscle hypoxia and lead to panic, and patients with coronary heart disease are usually accompanied by panic, palpitations, fatigue and shortness of breath and other symptoms. (2) asthma: asthma patients may appear chest tightness and shortness of breath, dyspnea can also lead to panic, palpitations, fatigue and other symptoms. If the symptoms of palpitations, panic, fatigue and shortness of breath, you should go to the hospital in time for targeted examination and treatment.