Mr. Zhao recently had a toothache when he exercised and became anxious, and he did not get better even after taking painkillers. After a comprehensive examination, he was found to have coronary heart disease, and the toothache gradually disappeared after taking coronary heart disease treatment drugs. Mr. Zhao was very puzzled: “It is said that the signs of coronary heart disease are heartache, panic, chest tightness and shortness of breath, but I don’t have these symptoms, either. Could it be that toothache is also a sign of coronary heart disease?” Chest pain, panic, palpitations, chest tightness and shortness of breath after exertion, emotional excitement or a full meal are all relatively common signs of coronary heart disease, and we all know them better. However, there are some manifestations that are less connected to the heart and people may ignore it, such as toothache. The heart itself has no painful nerves. Once the heart muscle is ischemic due to coronary heart disease, it accumulates many metabolites, such as lactic acid and other substances. These metabolites stimulate the heart’s vegetative nerves, and the stimulation signal is transmitted to the spinal cord center via the vegetative nerves, and the afferent spinal cord segments can be slightly different for different people, while the spinal cord center also receives afferent signals from the somatic sensory nerves, and when the spinal cord center receives the stimulation signal from the heart’s vegetative nerves, it will mistake the signal from the somatic sensory nerves in the corresponding area during processing and feel discomfort in these Since the afferent segment of the cardiac vegetative nerve is usually the afferent segment of the sensory nerve of the left chest and the left upper limb, most coronary heart patients have pain in the left chest or the left upper limb, but if the afferent segment of the cardiac vegetative nerve is high, they may have toothache or jaw pain. In the same way, if the afferent segment is low, it can be mistaken for a symptom of digestive tract disease, and in some people, it can also be manifested as shoulder and back pain. Therefore, if the symptoms of pain in the above mentioned areas occur in the presence of physical activity, a full meal, cold air stimulation, or emotional changes; and this pain will disappear within a few minutes after the trigger disappears, then it is likely to be a sign of coronary heart disease. People who have this signal should go to the hospital as soon as possible to receive a full examination, and should speak clearly with the doctor about the symptoms. If it is really coronary heart disease, it should be treated as soon as possible. In fact, the medical term angina is not necessarily the real “pain”, in the role of the above-mentioned triggers appear chest tightness, shortness of breath, breathing difficulties, pressure, tightness or other indefinable unpleasant feeling, if the attack trigger, duration, relief and other aspects consistent with the characteristics of angina symptoms, will also be diagnosed as angina All of these symptoms are called angina equivalent. If the angina or equivalent symptoms are new within the last month, or if there is a significant change in the attack pattern of the original symptoms within the last month, or if there is a significant decrease in activity tolerance, or if there is an attack of symptoms at rest, it is called ‘unstable angina’ and requires high attention and timely consultation.