The survival time of patients with advanced adenocarcinoma is uncertain and should be specifically analyzed according to the specific site where the adenocarcinoma occurs, whether there are distant metastases, and the method of treatment chosen. Adenocarcinoma mostly occurs in the lung, breast, gastrointestinal tract, pancreas, etc. The prognosis for patients with advanced adenocarcinoma is poor, and the survival period usually does not exceed six months to two years. If local metastasis of bones occurs in breast adenocarcinoma, the survival period may be about three years through endocrine therapy and radiotherapy. However, in case of advanced pancreatic adenocarcinoma, the survival period is usually six months to one year. The treatment of advanced lung adenocarcinoma mostly adopts targeted therapy, chemotherapy, immunotherapy, etc. The survival period is usually 1-2 years. For patients with advanced cancer, they should maintain an optimistic attitude and actively cooperate with doctors for comprehensive anti-tumor treatment to slow down the development of the disease and improve the quality of life.