The key to the treatment of diabetic leg neuropathy is to control blood sugar, and at the same time take treatments to improve blood circulation, nutritive nerves, analgesia and so on. 1. Control blood sugar: diabetic leg neuropathy belongs to one kind of diabetic complications, diabetic patients should take hypoglycemic drugs or choose subcutaneous insulin injection under doctor’s guidance, meanwhile combining with exercise and diet therapy to actively control blood sugar. 2. Nutrition of nerves and improvement of blood circulation: such as methylcobalamin tablets, vitamin B6, prostaglandin injection, etc. to improve the symptoms of leg neuropathy. 3. Analgesia: for diabetic neurogenic pain, drugs such as Pregabalin can be used for symptomatic treatment. Diabetic patients with complications should seek timely medical treatment, and medication should be prescribed by the doctor.