It is often said that “the left eye jumps for money and the right eye jumps for disaster”. In addition to blepharospasm, there is also a unilateral “eye jump” – facial myospasm. The facial muscle spasm is also a kind of focal dystonia, due to the facial nerve overexcitation caused by the paroxysmal, involuntary spasmodic contraction of the ipsilateral facial muscles, the spasm is usually limited to one side. Wuhan Union Hospital neurology Xiong Nian etiology, mainly (1) vascular factors: 80%-90% is caused by the facial nerve out of the brainstem area of vascular compression. Among them, such as posterior inferior cerebellar artery, anterior inferior cerebellar artery compression is the main; can also be caused by a single venous vascular compression. (2) Non-vascular factors: tumor, inflammation, cyst and arachnoid adhesions can cause facial muscle spasm. The prevalence is higher in women (14.5/100,000) than in men (7.4/100,000), and is higher in Asian (compared to Caucasian) populations. It is more common unilaterally at the age of 20-80 years, and 1/1000 is bilateral, and often occurs asymmetrically and asynchronously. The clinical features of facial myoclonus are: involuntary, painless, paroxysmal twitching of one side of the facial muscles; eyelid jumping —— initiating symptom, unilateral; ipsilateral cheek, corner of the mouth, and even neck muscle twitching; spastic eye closure, crooked and elevated corners of the mouth, may be accompanied by mild facial palsy, may involve the broad neck muscle, stapedius muscle; not accompanied by adjacent cranial nerve damage; stress, tension, chewing, speech, lighting, cold stimulation and fatigue It is aggravated by stress, tension, chewing, speech, light, cold stimulation, and fatigue, and relieved by quietness; some patients develop weakness and atrophy of the affected facial muscles and small eye fissures in late stages; it does not resolve on its own, but is not life-threatening; emotional stress, social and psychological disorders; and difficulty in speaking and reading. Facioscapulohumeral spasm requires MRI+MRA to make a definitive diagnosis, which can identify primary, vascular distortion, basilar aneurysm, AVM, ischemic changes, and tumorigenic lesions. Botulinum toxin local injection therapy: the first choice for symptomatic treatment (safe and effective, improves patient’s symptoms and quality of life) 2. The facial nerve root is exposed, the blood vessels compressing the facial nerve root are located and then freed, and the compressing vessels are padded away from the nerve with Teflon cotton. The most common complications are ipsilateral hearing impairment, facial palsy, and cerebrospinal fluid leakage, with an incidence of about 8% and rare (1%) brainstem stroke and death. Because of the potential and serious complications of surgery, it is usually considered only when the patient’s conservative treatment and repeated treatment with botulinum toxin have failed.4. Other: nerve block, muscle resection In conclusion, this “eye jump” – facial myasthenia – has been very difficult to treat in the past, with poor drug control and no specific treatment. Since the approval of botulinum toxin for facial spasms, it has brought a blessing to the majority of patients!