In medicine, pain is one of the most common symptoms, and the location of the pain often indicates where the lesion is located, while the nature of the pain indirectly indicates the type of pathological process. When you have pain, your body is reminding you that it is time to go to the doctor as soon as possible. A special word of caution here: if your pain always appears and worsens at night, then you may want to be especially vigilant because it carries some degree of risk of predicting the appearance of a tumor. This is not sensationalism. Just a short while ago we also saw several patients in our clinic in a row, one with lumbar spine pain, which was eventually found to be bone metastasis of lung cancer; and another with left abdominal pain, which was eventually found to be pancreatic cancer. In the case of tumor metastasis and general osteoarthrosis, although both problems are in the bone, there are differences in the manifestation of pain. Most of the pain caused by general osteoarthrosis is aggravated during daytime and activity, and reduced at night and during rest; however, the pain caused by tumor bone metastasis is obvious at night and even heavier than daytime, and rest does not relieve the pain. The same is true for abdominal pain. Most patients with pain caused by tumor also have more obvious pain at night, and the pain lasts for a long time, which cannot be relieved even by taking some drugs. Why do tumors cause more pain at night? It is not quite clear, maybe because the pain caused by tumor is always there, and at night we concentrate our mind, the pain feeling is more clear and prominent instead. Of course, not every night pain patient is necessarily a tumor patient, but if you continue to suffer from unexplained night pain, then you should indeed be alert. Do you know how to “see” pain? If you are going to see a pain specialist, please make sure to explain these questions to your doctor. 1. Where is your most painful area? The most painful point is probably where the primary lesion is located. 2. How long does your pain last? The time includes the point of each attack, the duration of the pain, and how long the pain has lasted since it first appeared, including the duration of the disease and the pattern of pain attacks. 3. How intense is your pain? Doctors will sometimes give you a scale from 1-10 to rate your pain, which can help them assess the intensity of your pain. Whether the pain interferes with sleep is also an important piece of information.4. What is the nature of your pain? Is it a sharp pain or a dull, dull ache? If the pain is pins and needles, fire, electric shock, or knife-like pain, then the pain is probably a neuropathic pain; if it is a dull, dull pain, many are related to internal diseases. 5. Have you used any means to stop the pain? If you have taken any medication, please tell your doctor and tell him/her how effective it is after taking the medication, which will help him/her to make further judgment.