Coronary artery spasm is a strong, spontaneous constriction of the coronary arteries that causes a transient narrowing or occlusion of the coronary arteries. Coronary artery spasm can resolve on its own or with the use of medications. Coronary artery spasms tend to occur in a localized area of the coronary artery, either in a completely normal coronary artery (about 30%) or more often in a segment with existing atherosclerosis, probably because such a segment is more susceptible to irritation. Calcium antagonists are effective drugs to relieve coronary artery spasm. Calcium antagonists can dilate small peripheral arteries, reduce the resistance of body circulation, reduce left ventricular afterload, reduce the work of left ventricular contraction, reduce oxygen consumption, inhibit the contraction of coronary vascular smooth muscle, dilate coronary arteries and release coronary artery spasm, and increase coronary artery blood flow. Some calcium antagonists can also slow heart rate, reduce oxygen consumption, and prolong diastolic coronary perfusion, while also inhibiting platelet aggregation and reducing the release of vasoconstrictor substances such as 5-hydroxytryptamine and TXA2. Therefore, calcium antagonists can be used for variant angina due to coronary artery spasm, such as Tenelheart 30 mg 3/day. after PTCA, to reduce coronary artery spasm, Tenelheart controlled-release tablets 90 mg 1/day can be used.